Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 567827..568343 Replicon chromosome
Accession NZ_CP124809
Organism Citrobacter freundii strain CF13

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QLG16_RS02880 Protein ID WP_044699148.1
Coordinates 568059..568343 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0J1MV10
Locus tag QLG16_RS02875 Protein ID WP_003839576.1
Coordinates 567827..568069 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLG16_RS02855 (562842) 562842..563975 + 1134 WP_016149471.1 amidohydrolase/deacetylase family metallohydrolase -
QLG16_RS02860 (563959) 563959..565077 + 1119 WP_044699152.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
QLG16_RS02865 (565074) 565074..565814 + 741 WP_044699149.1 KDGP aldolase family protein -
QLG16_RS02870 (565836) 565836..567749 + 1914 WP_003839574.1 BglG family transcription antiterminator -
QLG16_RS02875 (567827) 567827..568069 + 243 WP_003839576.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QLG16_RS02880 (568059) 568059..568343 + 285 WP_044699148.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QLG16_RS02885 (568347) 568347..568811 - 465 WP_032937736.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
QLG16_RS02890 (568918) 568918..571056 - 2139 WP_003025782.1 anaerobic ribonucleoside-triphosphate reductase -
QLG16_RS02895 (571434) 571434..572018 - 585 WP_003839584.1 fructose PTS transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10865.69 Da        Isoelectric Point: 10.1988

>T281243 WP_044699148.1 NZ_CP124809:568059-568343 [Citrobacter freundii]
MTYELEFDPRALKEWHKLGDTVKAQFKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDEVVTVFVVAVGK
RQHSAVYLDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT281243 WP_003839576.1 NZ_CP124809:567827-568069 [Citrobacter freundii]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTVSDSEDTLIQTVRERLASPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0J1MV10

References