281219

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1266220..1266710 Replicon chromosome
Accession NZ_CP124777
Organism Lachnoanaerobaculum gingivalis strain SHL-20230108WGSARO1-L360107582

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QJR73_RS05905 Protein ID WP_282670097.1
Coordinates 1266441..1266710 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID W2VCG7
Locus tag QJR73_RS05900 Protein ID WP_034213986.1
Coordinates 1266220..1266444 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJR73_RS05895 (QJR73_05895) 1265482..1266129 + 648 WP_282670096.1 hypothetical protein -
QJR73_RS05900 (QJR73_05900) 1266220..1266444 + 225 WP_034213986.1 DUF6290 family protein Antitoxin
QJR73_RS05905 (QJR73_05905) 1266441..1266710 + 270 WP_282670097.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QJR73_RS05910 (QJR73_05910) 1266786..1267142 + 357 WP_282670098.1 YlxM family DNA-binding protein -
QJR73_RS05915 (QJR73_05915) 1267152..1268507 + 1356 WP_282670099.1 signal recognition particle protein -
QJR73_RS05920 (QJR73_05920) 1268576..1268818 + 243 WP_007591924.1 30S ribosomal protein S16 -
QJR73_RS05925 (QJR73_05925) 1268831..1269058 + 228 WP_009218659.1 KH domain-containing protein -
QJR73_RS05930 (QJR73_05930) 1269136..1269645 + 510 WP_282670100.1 ribosome maturation factor RimM -
QJR73_RS05935 (QJR73_05935) 1269648..1270397 + 750 WP_282670101.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
QJR73_RS05940 (QJR73_05940) 1270390..1271502 + 1113 WP_282670102.1 DUF4317 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-87)

Antitoxin

Protein of unknown function DUF6290

(1-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10610.38 Da        Isoelectric Point: 10.1905

>T281219 WP_282670097.1 NZ_CP124777:1266441-1266710 [Lachnoanaerobaculum gingivalis]
MIYEISTTEKFDKALKKLDRQTQRIIKAWIEKNLINCENPRIHGKALTANRSGQWRYRVGDYRILAEIHDNKLVLILIDV
GHRKDIYLF

Download         Length: 270 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8787.06 Da        Isoelectric Point: 4.8723

>AT281219 WP_034213986.1 NZ_CP124777:1266220-1266444 [Lachnoanaerobaculum gingivalis]
MSVISLRVPENELNIFKSYAKHNNKSLSEIIRIAMLERIEDEYDLKVFEEYEAEKRSGTLKTRPISELWKDLDL

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB W2VCG7

References