Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3827652..3828308 Replicon chromosome
Accession NZ_CP124754
Organism Serratia sp. K-E0102

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SSARUM2_RS18230 Protein ID WP_060453052.1
Coordinates 3827652..3828041 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A8G2LCA8
Locus tag SSARUM2_RS18235 Protein ID WP_004941563.1
Coordinates 3828045..3828308 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SSARUM2_RS18215 (SSARUM2_003643) 3824119..3825549 + 1431 WP_060453051.1 MFS transporter -
SSARUM2_RS18220 (SSARUM2_003644) 3825546..3826928 + 1383 WP_033635541.1 two-component system sensor histidine kinase BaeS -
SSARUM2_RS18225 (SSARUM2_003645) 3826928..3827644 + 717 WP_033635542.1 two-component system response regulator BaeR -
SSARUM2_RS18230 (SSARUM2_003646) 3827652..3828041 - 390 WP_060453052.1 type II toxin-antitoxin system VapC family toxin Toxin
SSARUM2_RS18235 (SSARUM2_003647) 3828045..3828308 - 264 WP_004941563.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
SSARUM2_RS18240 (SSARUM2_003648) 3828648..3828986 + 339 WP_033648841.1 YegP family protein -
SSARUM2_RS18245 (SSARUM2_003649) 3829167..3830519 + 1353 WP_033635545.1 tRNA 5-hydroxyuridine modification protein YegQ -
SSARUM2_RS18250 (SSARUM2_003650) 3830986..3831891 + 906 WP_033635546.1 lipid kinase YegS -
SSARUM2_RS18255 (SSARUM2_003651) 3832181..3833230 + 1050 WP_033635553.1 class I fructose-bisphosphate aldolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14293.56 Da        Isoelectric Point: 7.7751

>T281214 WP_060453052.1 NZ_CP124754:c3828041-3827652 [Serratia sp. K-E0102]
MYMFDTNTVSHLFRQHPQVLNVMEKLPPSAVCISCVTEAELLYGVAKRRNKALQSVVEAFLAAVTVYAWDSEAARCYGEM
RANMEKKGKIMGALDQLIAAHAQSRGATLVTNDRAFAMVPGLAVEDWTR

Download         Length: 390 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10062.31 Da        Isoelectric Point: 4.6702

>AT281214 WP_004941563.1 NZ_CP124754:c3828308-3828045 [Serratia sp. K-E0102]
MERIAKLFKNGRNQAVRLPVEFEFDTDRVYIRRDREGNVILSKYPAKPDSWAPLLSIIAQTPVPQEFLGAEDRQQGVADR
DPFSEEE

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References