Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 39784..40319 Replicon plasmid pKM0706a
Accession NZ_CP124751
Organism Serratia sp. K-M0706

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SSARUM_RS24270 Protein ID WP_125460859.1
Coordinates 40032..40319 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SSARUM_RS24265 Protein ID WP_128884964.1
Coordinates 39784..40035 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SSARUM_RS24245 (SSARUM_004849) 35414..37462 + 2049 WP_128884960.1 ParB/RepB/Spo0J family partition protein -
SSARUM_RS24250 (SSARUM_004850) 37505..37969 + 465 WP_128884961.1 conjugation system SOS inhibitor PsiB -
SSARUM_RS24255 (SSARUM_004851) 37966..38730 + 765 WP_128884962.1 plasmid SOS inhibition protein A -
SSARUM_RS24260 (SSARUM_004852) 39249..39689 + 441 WP_128884963.1 dehydrogenase -
SSARUM_RS24265 (SSARUM_004853) 39784..40035 + 252 WP_128884964.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
SSARUM_RS24270 (SSARUM_004854) 40032..40319 + 288 WP_125460859.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SSARUM_RS24275 (SSARUM_004855) 40963..41421 + 459 WP_128884965.1 hypothetical protein -
SSARUM_RS24280 (SSARUM_004856) 41479..41628 + 150 WP_161568991.1 hypothetical protein -
SSARUM_RS24285 (SSARUM_004857) 42090..42911 + 822 WP_128885025.1 DUF932 domain-containing protein -
SSARUM_RS24290 (SSARUM_004858) 42934..43260 + 327 WP_128884966.1 DUF5983 family protein -
SSARUM_RS24295 (SSARUM_004859) 43332..43646 - 315 WP_238476108.1 mobilization protein MobC -
SSARUM_RS24300 (SSARUM_004860) 43920..44261 + 342 WP_128884967.1 plasmid mobilization protein MobA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..83787 83787


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10891.93 Da        Isoelectric Point: 10.2278

>T281202 WP_125460859.1 NZ_CP124751:40032-40319 [Serratia sp. K-M0706]
MTYTVKFRESALKEWGKLDKSLQQQFAKKLKKCCENPHIPSAKLRGMPGCYKIKLRASGFRLVYEVIDDCLIIAVVAVGK
RERGDVYQLASERLK

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9154.45 Da        Isoelectric Point: 4.0338

>AT281202 WP_128884964.1 NZ_CP124751:39784-40035 [Serratia sp. K-M0706]
MPNIILSDTSASISELKKNPMETVGAGAGFPVAILNRNKPEFYCVPAALYEQMLDALDDQELVKLVNERRSEALVDIDLD
QFA

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References