Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4095952..4096621 Replicon chromosome
Accession NZ_CP124750
Organism Serratia sp. K-M0706

Toxin (Protein)


Gene name cptA Uniprot ID A0A2V4FX75
Locus tag SSARUM_RS19420 Protein ID WP_033649453.1
Coordinates 4095952..4096374 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag SSARUM_RS19425 Protein ID WP_004931679.1
Coordinates 4096355..4096621 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SSARUM_RS19400 (SSARUM_003880) 4091841..4092359 + 519 WP_033635825.1 flavodoxin FldB -
SSARUM_RS19405 (SSARUM_003881) 4092397..4093761 - 1365 WP_060431066.1 cell envelope integrity protein CreD -
SSARUM_RS19410 (SSARUM_003882) 4093842..4095260 - 1419 WP_033649455.1 two-component system sensor histidine kinase CreC -
SSARUM_RS19415 (SSARUM_003883) 4095257..4095952 - 696 WP_033649454.1 two-component system response regulator CreB -
SSARUM_RS19420 (SSARUM_003884) 4095952..4096374 - 423 WP_033649453.1 protein YgfX Toxin
SSARUM_RS19425 (SSARUM_003885) 4096355..4096621 - 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
SSARUM_RS19430 (SSARUM_003886) 4096942..4097934 + 993 WP_033649452.1 tRNA-modifying protein YgfZ -
SSARUM_RS19435 (SSARUM_003887) 4097973..4098470 - 498 WP_033649451.1 DUF2165 domain-containing protein -
SSARUM_RS19440 (SSARUM_003888) 4098621..4099295 - 675 WP_033649450.1 hemolysin III family protein -
SSARUM_RS19445 (SSARUM_003889) 4099479..4100087 + 609 WP_025304127.1 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16471.59 Da        Isoelectric Point: 10.8114

>T281200 WP_033649453.1 NZ_CP124750:c4096374-4095952 [Serratia sp. K-M0706]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAAQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLLPMEGKKRRRLWLASDCMSKEEWRHLRQLLLYPPAGDGEDP

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT281200 WP_004931679.1 NZ_CP124750:c4096621-4096355 [Serratia sp. K-M0706]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2V4FX75

Antitoxin

Source ID Structure

References