Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 55058..55593 Replicon chromosome
Accession NZ_CP124750
Organism Serratia sp. K-M0706

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SSARUM_RS00250 Protein ID WP_033649525.1
Coordinates 55318..55593 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SSARUM_RS00245 Protein ID WP_033649526.1
Coordinates 55058..55318 (+) Length 87 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SSARUM_RS00225 (SSARUM_000045) 50377..51027 + 651 WP_033649530.1 DcrB-related protein -
SSARUM_RS00230 (SSARUM_000046) 51068..51673 + 606 WP_033649529.1 glutathione S-transferase -
SSARUM_RS00235 (SSARUM_000047) 51743..53137 + 1395 WP_033649528.1 L-seryl-tRNA(Sec) selenium transferase -
SSARUM_RS00240 (SSARUM_000048) 53134..54975 + 1842 WP_033649527.1 selenocysteine-specific translation elongation factor -
SSARUM_RS00245 (SSARUM_000049) 55058..55318 + 261 WP_033649526.1 ribbon-helix-helix domain-containing protein Antitoxin
SSARUM_RS00250 (SSARUM_000050) 55318..55593 + 276 WP_033649525.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SSARUM_RS00255 (SSARUM_000051) 55605..56516 - 912 WP_033636572.1 LysR family transcriptional regulator -
SSARUM_RS00260 (SSARUM_000052) 56638..57264 + 627 WP_033649524.1 LysE family translocator -
SSARUM_RS00265 (SSARUM_000053) 57318..58565 - 1248 WP_033649577.1 MFS transporter -
SSARUM_RS00270 (SSARUM_000054) 58783..59775 + 993 WP_033649523.1 acyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 92 a.a.        Molecular weight: 10596.34 Da        Isoelectric Point: 10.3377

>T281187 WP_033649525.1 NZ_CP124750:55318-55593 [Serratia sp. K-M0706]
MELKWTSKALSDLARLFEFLALVNRTAAANSVKALVAAPKALLDNSRLGERLDEFLPQEVRRILVGRYEIRYQVQPATIY
VLRIWHTREER

Download         Length: 276 bp


Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9698.01 Da        Isoelectric Point: 4.5201

>AT281187 WP_033649526.1 NZ_CP124750:55058-55318 [Serratia sp. K-M0706]
MNTKVITAHVPLPLAEKVDEMAAKLERSRGWIVKQALTAWLEQEEERRRLTLAALADVEQQNVIDHESVEAWAASLDSDD
PLPVPR

Download         Length: 261 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References