Detailed information of TA system TA028117

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasABC/RelE-HTH
• Location: 646..1138
• Replicon: plasmid pZZ6.03
• Accession: NC_018148
• Organism: Zymomonas mobilis subsp. mobilis ATCC 29191

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: -
• Locus tag: ZZ6_RS09150
• Protein ID: WP_014849512.1
• Coordinates: 646..930 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: ZZ6_RS09155
• Protein ID: WP_014849513.1
• Coordinates: 914..1138 (-)
• Length: 75 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ZZ6_RS09145	131..358	+	228	WP_014849511.1	hypothetical protein	-
ZZ6_RS09150	646..930	-	285	WP_014849512.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ZZ6_RS09155	914..1138	-	225	WP_014849513.1	TraY domain-containing protein	Antitoxin
ZZ6_RS09530	1336..1494	+	159	Protein_3	transposase	-
ZZ6_RS09160	1750..3276	+	1527	WP_014849514.1	type I restriction-modification system subunit M	-
ZZ6_RS09165	3266..4420	+	1155	WP_014849515.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..13742	13742

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-88)

Antitoxin

• Relaxosome protein TraY (4-49)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10843.83 Da
• Isoelectric Point: 10.9851

>T28117 WP_014849512.1 NC_018148:c930-646 [Zymomonas mobilis subsp. mobilis ATCC 29191]
MAWKIEFDPAAQKELKKLGTQHAKRILKFLSERLALADNPRSLGAALKGATLGSLWKYRIGDYRVIVDIEDNVMRILVVR
IGNRREIYKKAIRH

Nucleotide

• Length: 285 bp

>T28117 NC_018148:c930-646 [Zymomonas mobilis subsp. mobilis ATCC 29191]
ATGGCTTGGAAAATTGAATTCGATCCAGCTGCCCAAAAAGAGTTAAAAAAACTAGGAACACAGCACGCTAAGCGTATTTT
AAAATTTTTATCTGAACGTTTGGCATTGGCTGATAACCCAAGGTCACTAGGCGCGGCTTTAAAAGGAGCTACGCTAGGTA
GCTTATGGAAATATCGAATCGGAGATTACCGCGTTATTGTCGACATTGAAGATAACGTGATGCGAATTCTGGTCGTCAGA
ATTGGTAATAGAAGAGAAATTTATAAAAAAGCTATTAGGCATTAA

Antitoxin

Protein

• Length: 75 a.a.
• Molecular weight: 8420.65 Da
• Isoelectric Point: 5.6122

>AT28117 WP_014849513.1 NC_018148:c1138-914 [Zymomonas mobilis subsp. mobilis ATCC 29191]
MLAIRLPEEIENRLSALANATGRTKTFYAREAILHHLEELEDIYLAEARAIKIRSGHTKTVPLENIMAEYGLEN

Nucleotide

• Length: 225 bp

>AT28117 NC_018148:c1138-914 [Zymomonas mobilis subsp. mobilis ATCC 29191]
ATGTTAGCAATTAGATTACCAGAAGAAATAGAAAACCGATTAAGTGCGTTGGCCAATGCAACAGGTCGAACTAAGACTTT
TTATGCAAGAGAGGCTATACTTCACCATTTAGAAGAGCTCGAGGATATTTATTTAGCCGAAGCTCGTGCAATAAAAATTC
GTTCTGGCCACACGAAGACTGTCCCGTTAGAAAATATTATGGCTGAATATGGCTTGGAAAATTGA