Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4848717..4848988 Replicon chromosome
Accession NZ_CP124740
Organism Escherichia coli O157:H7 str. EDL933

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4848847..4848950 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4848717..4848988 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QI555_RS23970 4845272..4845934 - 663 WP_000944243.1 exodeoxyribonuclease X -
QI555_RS23975 4845958..4846614 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
QI555_RS23980 4846716..4846946 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QI555_RS23985 4847085..4847459 + 375 WP_000168751.1 CopC domain-containing protein YobA -
QI555_RS23990 4847463..4848335 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
QI555_RS23995 4848348..4848689 + 342 WP_000976483.1 YebY family protein -
- 4848717..4848988 - 272 - - Antitoxin
- 4848847..4848950 + 104 - - Toxin
QI555_RS24000 4849085..4849741 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
QI555_RS24005 4849742..4849933 - 192 WP_001296140.1 YebW family protein -
QI555_RS24010 4850038..4850274 - 237 WP_001295499.1 YebV family protein -
QI555_RS24015 4850392..4851831 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T281166 NZ_CP124740:4848847-4848950 [Escherichia coli O157:H7 str. EDL933]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT281166 NZ_CP124740:c4848988-4848717 [Escherichia coli O157:H7 str. EDL933]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References