Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2445937..2446475 Replicon chromosome
Accession NZ_CP124733
Organism Agrobacterium larrymoorei strain CFBP5477

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CFBP5477_RS11965 Protein ID WP_137392674.1
Coordinates 2446182..2446475 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag CFBP5477_RS11960 Protein ID WP_137392673.1
Coordinates 2445937..2446185 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5477_RS11925 (CFBP5477_011925) 2441434..2441922 - 489 WP_137392669.1 DUF1579 domain-containing protein -
CFBP5477_RS11930 (CFBP5477_011930) 2441936..2442664 - 729 WP_137392670.1 thioredoxin family protein -
CFBP5477_RS11935 (CFBP5477_011935) 2442784..2443230 + 447 WP_137392671.1 MarR family winged helix-turn-helix transcriptional regulator -
CFBP5477_RS11940 (CFBP5477_011940) 2443461..2444225 - 765 WP_170980104.1 RES family NAD+ phosphorylase -
CFBP5477_RS11945 (CFBP5477_011945) 2444185..2444568 - 384 WP_027675631.1 MbcA/ParS/Xre antitoxin family protein -
CFBP5477_RS11950 (CFBP5477_011950) 2444692..2445117 - 426 WP_027675632.1 organic hydroperoxide resistance protein -
CFBP5477_RS11955 (CFBP5477_011955) 2445312..2445773 + 462 WP_137392672.1 MarR family transcriptional regulator -
CFBP5477_RS11960 (CFBP5477_011960) 2445937..2446185 + 249 WP_137392673.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
CFBP5477_RS11965 (CFBP5477_011965) 2446182..2446475 + 294 WP_137392674.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFBP5477_RS11970 (CFBP5477_011970) 2446533..2446868 - 336 WP_197736736.1 NINE protein -
CFBP5477_RS11975 (CFBP5477_011975) 2447002..2447736 - 735 WP_027675637.1 L,D-transpeptidase -
CFBP5477_RS11980 (CFBP5477_011980) 2447937..2448821 - 885 WP_137392675.1 L,D-transpeptidase -
CFBP5477_RS11985 (CFBP5477_011985) 2448935..2449876 - 942 WP_137392676.1 prolyl oligopeptidase family serine peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

Antitoxin ParD

(1-81)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11084.53 Da        Isoelectric Point: 6.4764

>T281144 WP_137392674.1 NZ_CP124733:2446182-2446475 [Agrobacterium larrymoorei]
MKALALSPAAEADLDYIWEHSATNWGLDQADRYTDEIRDACLNLAAGVRHGRPVDVRSGYLKFATGTHMIYFRDQGDRLD
IVRILHQRQDVIFNLPK

Download         Length: 294 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9149.14 Da        Isoelectric Point: 6.4680

>AT281144 WP_137392673.1 NZ_CP124733:2445937-2446185 [Agrobacterium larrymoorei]
MARNTSITLGDHFASFISDQVQTGRYGSTSDVVRAGLRLLEEHEAKVKSLQDALIAGEQSGEPRAFDFEAFKARKRTEYE
GR

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References