Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 2401389..2401861 Replicon chromosome
Accession NZ_CP124733
Organism Agrobacterium larrymoorei strain CFBP5477

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag CFBP5477_RS11685 Protein ID WP_234882834.1
Coordinates 2401389..2401535 (+) Length 49 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag CFBP5477_RS11690 Protein ID WP_170980103.1
Coordinates 2401532..2401861 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5477_RS11660 (CFBP5477_011660) 2397025..2397525 - 501 WP_137392628.1 GNAT family N-acetyltransferase -
CFBP5477_RS11665 (CFBP5477_011665) 2397610..2398281 - 672 WP_027677177.1 hemolysin III family protein -
CFBP5477_RS11670 (CFBP5477_011670) 2398399..2398809 - 411 WP_137392629.1 universal stress protein -
CFBP5477_RS11675 (CFBP5477_011675) 2399039..2399899 + 861 WP_137392630.1 VOC family protein -
CFBP5477_RS11680 (CFBP5477_011680) 2400049..2401167 + 1119 WP_051441439.1 AI-2E family transporter -
CFBP5477_RS11685 (CFBP5477_011685) 2401389..2401535 + 147 WP_234882834.1 type II toxin-antitoxin system HicA family toxin Toxin
CFBP5477_RS11690 (CFBP5477_011690) 2401532..2401861 + 330 WP_170980103.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
CFBP5477_RS11695 (CFBP5477_011695) 2401864..2402586 - 723 WP_137392631.1 polysaccharide deacetylase family protein -
CFBP5477_RS11700 (CFBP5477_011700) 2402641..2403561 - 921 WP_137392632.1 dihydrodipicolinate synthase family protein -
CFBP5477_RS11705 (CFBP5477_011705) 2403886..2404284 - 399 WP_027677339.1 DUF930 domain-containing protein -
CFBP5477_RS11710 (CFBP5477_011710) 2404520..2406619 + 2100 WP_137393396.1 S9 family peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(5-46)

Antitoxin

Uncharacterised protein family HicB

(54-104)


Sequences

Toxin        


Download         Length: 49 a.a.        Molecular weight: 5286.07 Da        Isoelectric Point: 12.1410

>T281143 WP_234882834.1 NZ_CP124733:2401389-2401535 [Agrobacterium larrymoorei]
ISEGSGSRVRVALNGMRAVFHRPHPQKETDKGAVKSVRRFLSEAGIRP

Download         Length: 147 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12251.79 Da        Isoelectric Point: 4.7809

>AT281143 WP_170980103.1 NZ_CP124733:2401532-2401861 [Agrobacterium larrymoorei]
MTLMHYKGYEAVIEFDEDAEIFHGEVINLRDVITFQGSSAAELKQALAESVEDYISFCKERGEEPEKPFSGQFVVRAEPR
LHKAISTAARRDGVSLNKWVTSTLEKAVS

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References