Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 1372528..1373072 Replicon chromosome
Accession NZ_CP124733
Organism Agrobacterium larrymoorei strain CFBP5477

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag CFBP5477_RS06480 Protein ID WP_137394155.1
Coordinates 1372749..1373072 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag CFBP5477_RS06475 Protein ID WP_137394154.1
Coordinates 1372528..1372752 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5477_RS06455 (CFBP5477_006455) 1367632..1369398 + 1767 WP_137394150.1 penicillin-binding protein 2 -
CFBP5477_RS06460 (CFBP5477_006460) 1369392..1370603 - 1212 WP_137394151.1 MFS transporter -
CFBP5477_RS06465 (CFBP5477_006465) 1370675..1371583 - 909 WP_137394152.1 LysR family transcriptional regulator -
CFBP5477_RS06470 (CFBP5477_006470) 1371681..1372430 + 750 WP_137394153.1 sulfite exporter TauE/SafE family protein -
CFBP5477_RS06475 (CFBP5477_006475) 1372528..1372752 + 225 WP_137394154.1 antitoxin MazE family protein Antitoxin
CFBP5477_RS06480 (CFBP5477_006480) 1372749..1373072 + 324 WP_137394155.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
CFBP5477_RS06485 (CFBP5477_006485) 1373108..1373401 - 294 WP_027677142.1 hypothetical protein -
CFBP5477_RS06490 (CFBP5477_006490) 1373962..1374333 + 372 WP_003507760.1 30S ribosomal protein S12 -
CFBP5477_RS06495 (CFBP5477_006495) 1374411..1374881 + 471 WP_027677141.1 30S ribosomal protein S7 -
CFBP5477_RS06500 (CFBP5477_006500) 1374909..1377008 + 2100 WP_027677140.1 elongation factor G -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-102)

Antitoxin

Antitoxin MazE-like

(6-71)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11549.46 Da        Isoelectric Point: 9.9929

>T281139 WP_137394155.1 NZ_CP124733:1372749-1373072 [Agrobacterium larrymoorei]
VRRGDLVTVSVSGDFGKPRPALVIQSDYFSETATVTVLLVSGTLVDAPFIRLTIQPSSRNGLVKPSQVMIDKPMTVLREK
VGQSFGRLEDDVMLSVTRSLAVFVGLA

Download         Length: 324 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8275.20 Da        Isoelectric Point: 5.5874

>AT281139 WP_137394154.1 NZ_CP124733:1372528-1372752 [Agrobacterium larrymoorei]
MATTVNHRVQKRREALRASGLRPVQIWVPDTRLAGFAEECRRQSHLVAELDHQDAEFAAFADAALSDLDDEGSK

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References