Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1337864..1338383 Replicon chromosome
Accession NZ_CP124733
Organism Agrobacterium larrymoorei strain CFBP5477

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CFBP5477_RS06295 Protein ID WP_137394136.1
Coordinates 1338102..1338383 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CFBP5477_RS06290 Protein ID WP_137394135.1
Coordinates 1337864..1338112 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5477_RS06275 (CFBP5477_006275) 1333866..1336916 - 3051 WP_137394133.1 excinuclease ABC subunit UvrB -
CFBP5477_RS06280 (CFBP5477_006280) 1336962..1337450 - 489 WP_170980186.1 hypothetical protein -
CFBP5477_RS06285 (CFBP5477_006285) 1337383..1337736 + 354 WP_027676067.1 DMT family protein -
CFBP5477_RS06290 (CFBP5477_006290) 1337864..1338112 + 249 WP_137394135.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CFBP5477_RS06295 (CFBP5477_006295) 1338102..1338383 + 282 WP_137394136.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFBP5477_RS06300 (CFBP5477_006300) 1338388..1338849 + 462 WP_234882881.1 GNAT family N-acetyltransferase -
CFBP5477_RS06305 (CFBP5477_006305) 1338989..1339414 - 426 WP_137394206.1 MarR family transcriptional regulator -
CFBP5477_RS06310 (CFBP5477_006310) 1339469..1339864 - 396 WP_137394137.1 multidrug efflux SMR transporter -
CFBP5477_RS06315 (CFBP5477_006315) 1339888..1340223 - 336 WP_234882883.1 multidrug efflux SMR transporter -
CFBP5477_RS06320 (CFBP5477_006320) 1340482..1341924 - 1443 WP_137394138.1 PepSY domain-containing protein -
CFBP5477_RS06325 (CFBP5477_006325) 1342010..1342414 - 405 WP_137394139.1 DUF2946 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1331009..1340208 9199


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10805.59 Da        Isoelectric Point: 10.6956

>T281138 WP_137394136.1 NZ_CP124733:1338102-1338383 [Agrobacterium larrymoorei]
MSYELGFVDAALKEWRKLDSNTQEQFKKKLAERLVNPRVPAAKLSGHSDRYKIKLRGAGYRLVYEVRDKEVLVLVVAVGR
RDRDQVYKLAAKR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8845.12 Da        Isoelectric Point: 4.2404

>AT281138 WP_137394135.1 NZ_CP124733:1337864-1338112 [Agrobacterium larrymoorei]
MAHVVLAEMTASVSELKKNPMGTVAAGDGAPVAILNRNEPAFYCVPAKAYEAMMERLDDIELNAIADSRADQPVTRVQLD
EL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References