Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 853566..854151 Replicon chromosome
Accession NZ_CP124733
Organism Agrobacterium larrymoorei strain CFBP5477

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CFBP5477_RS04015 Protein ID WP_137393794.1
Coordinates 853864..854151 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CFBP5477_RS04010 Protein ID WP_137393793.1
Coordinates 853566..853862 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5477_RS03990 (CFBP5477_003990) 849657..850964 - 1308 WP_137393790.1 guanine deaminase -
CFBP5477_RS03995 (CFBP5477_003995) 850961..852208 - 1248 WP_137393791.1 urate hydroxylase PuuD -
CFBP5477_RS04000 (CFBP5477_004000) 852323..853216 - 894 WP_137393792.1 transcriptional regulator GcvA -
CFBP5477_RS04005 (CFBP5477_004005) 853321..853551 + 231 WP_027676623.1 hypothetical protein -
CFBP5477_RS04010 (CFBP5477_004010) 853566..853862 - 297 WP_137393793.1 putative addiction module antidote protein Antitoxin
CFBP5477_RS04015 (CFBP5477_004015) 853864..854151 - 288 WP_137393794.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFBP5477_RS04020 (CFBP5477_004020) 854199..855026 - 828 WP_137393795.1 xanthine dehydrogenase accessory protein XdhC -
CFBP5477_RS04025 (CFBP5477_004025) 855036..857375 - 2340 WP_170980168.1 xanthine dehydrogenase molybdopterin binding subunit -
CFBP5477_RS04030 (CFBP5477_004030) 857582..859048 - 1467 WP_137393796.1 xanthine dehydrogenase small subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-89)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11066.88 Da        Isoelectric Point: 10.6020

>T281135 WP_137393794.1 NZ_CP124733:c854151-853864 [Agrobacterium larrymoorei]
MIRIRKTNIFSDWFTSLRDRRAQARIQVRIDRLSLGLLGDVKFFDGIGEMRIDYGPGYRVYFMRRQNEIVILLCGGDKGS
QTRDIERAIKIAAEV

Download         Length: 288 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10490.08 Da        Isoelectric Point: 4.8146

>AT281135 WP_137393793.1 NZ_CP124733:c853862-853566 [Agrobacterium larrymoorei]
MKVEVTDWDTSDYLNGNEAMIAYLEASFEDGDPKVIAMALGNIAKAKGMSQVAKQAGITREALYKSLSEKGDPKLSTLIG
VMKALGLRLSVAPEERAA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References