Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 843739..844335 Replicon chromosome
Accession NZ_CP124733
Organism Agrobacterium larrymoorei strain CFBP5477

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CFBP5477_RS03970 Protein ID WP_282503319.1
Coordinates 844042..844335 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CFBP5477_RS03965 Protein ID WP_137393786.1
Coordinates 843739..843990 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5477_RS03925 (CFBP5477_003925) 839138..839845 + 708 WP_137393778.1 DUF1045 domain-containing protein -
CFBP5477_RS03930 (CFBP5477_003930) 839924..840847 + 924 WP_137393779.1 allantoinase PuuE -
CFBP5477_RS03935 (CFBP5477_003935) 840844..841347 + 504 WP_137393780.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase -
CFBP5477_RS03940 (CFBP5477_003940) 841413..841706 + 294 WP_137393781.1 nucleotidyltransferase family protein -
CFBP5477_RS03945 (CFBP5477_003945) 841703..842065 + 363 WP_137393782.1 DUF86 domain-containing protein -
CFBP5477_RS03950 (CFBP5477_003950) 842082..842582 + 501 WP_137393783.1 ureidoglycolate lyase -
CFBP5477_RS03955 (CFBP5477_003955) 842579..842935 + 357 WP_137393784.1 hydroxyisourate hydrolase -
CFBP5477_RS03960 (CFBP5477_003960) 842941..843681 + 741 WP_137393785.1 metallophosphoesterase family protein -
CFBP5477_RS03965 (CFBP5477_003965) 843739..843990 + 252 WP_137393786.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CFBP5477_RS03970 (CFBP5477_003970) 844042..844335 + 294 WP_282503319.1 Txe/YoeB family addiction module toxin Toxin
CFBP5477_RS03975 (CFBP5477_003975) 844347..845615 - 1269 WP_137393787.1 D-alanyl-D-alanine carboxypeptidase -
CFBP5477_RS03980 (CFBP5477_003980) 846045..847187 - 1143 WP_170980167.1 alpha-hydroxy acid oxidase -
CFBP5477_RS03985 (CFBP5477_003985) 847374..849326 - 1953 WP_137393789.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(14-97)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11634.44 Da        Isoelectric Point: 9.7522

>T281134 WP_282503319.1 NZ_CP124733:844042-844335 [Agrobacterium larrymoorei]
MPHGEKSSEILLSWTSKGWEDYLYWQQADKKVLVRINELIRDALRHPFEGIGKPEPLRFNLKGLWSRRITQEHRLIYAIR
GEGDRRTLVILQCLYHY

Download         Length: 294 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9488.71 Da        Isoelectric Point: 4.2904

>AT281134 WP_137393786.1 NZ_CP124733:843739-843990 [Agrobacterium larrymoorei]
MRTVMFSTARSELSTLLDEVSHDRVAVEIVRRDKPSAILIDKNEYEGLMETLHLYSSPANIGRLMEAMDELEKGDYQQSD
LID

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References