Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VagC
Location 711741..712405 Replicon chromosome
Accession NZ_CP124733
Organism Agrobacterium larrymoorei strain CFBP5477

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CFBP5477_RS03290 Protein ID WP_137393701.1
Coordinates 711741..712142 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CFBP5477_RS03295 Protein ID WP_137393702.1
Coordinates 712142..712405 (-) Length 88 a.a.

Genomic Context

CFBP5477_RS03270CFBP5477_RS03275CFBP5477_RS03280CFBP5477_RS03285CFBP5477_RS03290CFBP5477_RS03295CFBP5477_RS03300
Location: 707277..708512 (1236 bp)
Type: Others
Protein ID: WP_027675557.1
Location: 708593..709825 (1233 bp)
Type: Others
Protein ID: WP_027675558.1
Location: 710001..710186 (186 bp)
Type: Others
Protein ID: WP_027675559.1
Location: 710263..711720 (1458 bp)
Type: Others
Protein ID: WP_137393700.1
Location: 711741..712142 (402 bp)
Type: Toxin
Protein ID: WP_137393701.1
Location: 712142..712405 (264 bp)
Type: Antitoxin
Protein ID: WP_137393702.1
Location: 712464..717206 (4743 bp)
Type: Others
Protein ID: WP_137393703.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CFBP5477_RS03270 (CFBP5477_003270)707277..708512+1236WP_027675557.1lytic murein transglycosylase-
CFBP5477_RS03275 (CFBP5477_003275)708593..709825+1233WP_027675558.1DUF459 domain-containing protein-
CFBP5477_RS03280 (CFBP5477_003280)710001..710186+186WP_027675559.1hypothetical protein-
CFBP5477_RS03285 (CFBP5477_003285)710263..711720-1458WP_137393700.1glutamate synthase subunit beta-
CFBP5477_RS03290 (CFBP5477_003290)711741..712142-402WP_137393701.1type II toxin-antitoxin system VapC family toxinToxin
CFBP5477_RS03295 (CFBP5477_003295)712142..712405-264WP_137393702.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
CFBP5477_RS03300 (CFBP5477_003300)712464..717206-4743WP_137393703.1glutamate synthase large subunit-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin

SpoVT-AbrB domain

(14-52)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14997.14 Da        Isoelectric Point: 6.0844

>T281133 WP_137393701.1 NZ_CP124733:c712142-711741 [Agrobacterium larrymoorei]
MRYLLDTNAISHVIDFPTGSVAQRIRTEAVTGTLVTSVIVVAELRYGYTKISSQRLRDAYETFFESLPIENWEAPFDHVY
ADIRDQLTKKGRSIGAMDMLIAAHALATDAVVVTANIKHFSEVPELKVENWLR

Download         Length: 402 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10003.48 Da        Isoelectric Point: 4.7370

>AT281133 WP_137393702.1 NZ_CP124733:c712405-712142 [Agrobacterium larrymoorei]
MVAVIEKEVSVFNNGRSRAVRIPSDFKLEGDSVLMSQDEDGVIHIRPKKPKKSLLEVLDWLAKQEPFEERMPEIEDYPPE
PVDLGKR

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References