Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VagC
Location 711741..712405 Replicon chromosome
Accession NZ_CP124733
Organism Agrobacterium larrymoorei strain CFBP5477

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CFBP5477_RS03290 Protein ID WP_137393701.1
Coordinates 711741..712142 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CFBP5477_RS03295 Protein ID WP_137393702.1
Coordinates 712142..712405 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5477_RS03270 (CFBP5477_003270) 707277..708512 + 1236 WP_027675557.1 lytic murein transglycosylase -
CFBP5477_RS03275 (CFBP5477_003275) 708593..709825 + 1233 WP_027675558.1 DUF459 domain-containing protein -
CFBP5477_RS03280 (CFBP5477_003280) 710001..710186 + 186 WP_027675559.1 hypothetical protein -
CFBP5477_RS03285 (CFBP5477_003285) 710263..711720 - 1458 WP_137393700.1 glutamate synthase subunit beta -
CFBP5477_RS03290 (CFBP5477_003290) 711741..712142 - 402 WP_137393701.1 type II toxin-antitoxin system VapC family toxin Toxin
CFBP5477_RS03295 (CFBP5477_003295) 712142..712405 - 264 WP_137393702.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CFBP5477_RS03300 (CFBP5477_003300) 712464..717206 - 4743 WP_137393703.1 glutamate synthase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin

SpoVT-AbrB domain

(14-52)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14997.14 Da        Isoelectric Point: 6.0844

>T281133 WP_137393701.1 NZ_CP124733:c712142-711741 [Agrobacterium larrymoorei]
MRYLLDTNAISHVIDFPTGSVAQRIRTEAVTGTLVTSVIVVAELRYGYTKISSQRLRDAYETFFESLPIENWEAPFDHVY
ADIRDQLTKKGRSIGAMDMLIAAHALATDAVVVTANIKHFSEVPELKVENWLR

Download         Length: 402 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10003.48 Da        Isoelectric Point: 4.7370

>AT281133 WP_137393702.1 NZ_CP124733:c712405-712142 [Agrobacterium larrymoorei]
MVAVIEKEVSVFNNGRSRAVRIPSDFKLEGDSVLMSQDEDGVIHIRPKKPKKSLLEVLDWLAKQEPFEERMPEIEDYPPE
PVDLGKR

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References