281131

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6784601..6785190 Replicon chromosome
Accession NZ_CP124732
Organism Pseudomonas sp. GM17

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PMI20_RS30345 Protein ID WP_007924097.1
Coordinates 6784891..6785190 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PMI20_RS30340 Protein ID WP_007924096.1
Coordinates 6784601..6784894 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PMI20_RS30315 (PMI20_030315) 6780363..6780821 + 459 WP_007924092.1 GNAT family N-acetyltransferase -
PMI20_RS30320 (PMI20_030320) 6781074..6781730 + 657 WP_007924093.1 DedA family protein -
PMI20_RS30325 (PMI20_030325) 6781736..6782542 + 807 WP_007924094.1 zinc-dependent peptidase -
PMI20_RS30330 (PMI20_030330) 6782807..6783334 + 528 WP_003228599.1 inorganic diphosphatase -
PMI20_RS30335 (PMI20_030335) 6784142..6784488 + 347 Protein_5984 hypothetical protein -
PMI20_RS30340 (PMI20_030340) 6784601..6784894 - 294 WP_007924096.1 putative addiction module antidote protein Antitoxin
PMI20_RS30345 (PMI20_030345) 6784891..6785190 - 300 WP_007924097.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PMI20_RS30350 (PMI20_030350) 6785362..6785811 + 450 WP_007924098.1 DUF3828 domain-containing protein -
PMI20_RS30355 (PMI20_030355) 6785836..6786846 - 1011 WP_177323786.1 NAD(P)-dependent alcohol dehydrogenase -
PMI20_RS30360 (PMI20_030360) 6786904..6787203 - 300 WP_007924100.1 helix-turn-helix transcriptional regulator -
PMI20_RS30365 (PMI20_030365) 6787270..6788358 - 1089 WP_007924101.1 copper-containing nitrite reductase -
PMI20_RS30370 (PMI20_030370) 6788585..6788827 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PMI20_RS30375 (PMI20_030375) 6788824..6789711 + 888 WP_007924103.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11326.08 Da        Isoelectric Point: 10.6613

>T281131 WP_007924097.1 NZ_CP124732:c6785190-6784891 [Pseudomonas sp. GM17]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQRGLQLVILLCGGDKS
RQSRDIELAKYLARRWSRS

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10430.94 Da        Isoelectric Point: 5.6558

>AT281131 WP_007924096.1 NZ_CP124732:c6784894-6784601 [Pseudomonas sp. GM17]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References