Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4820598..4821117 Replicon chromosome
Accession NZ_CP124732
Organism Pseudomonas sp. GM17

Toxin (Protein)


Gene name relE Uniprot ID A0A1H3UB31
Locus tag PMI20_RS21495 Protein ID WP_007930524.1
Coordinates 4820598..4820879 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3G7HDX0
Locus tag PMI20_RS21500 Protein ID WP_007930518.1
Coordinates 4820869..4821117 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PMI20_RS21470 (PMI20_021470) 4815806..4816078 + 273 WP_007927368.1 hypothetical protein -
PMI20_RS21475 (PMI20_021475) 4816777..4816882 - 106 Protein_4244 AAA family ATPase -
PMI20_RS21480 (PMI20_021480) 4816970..4817761 + 792 WP_007930528.1 methyltransferase domain-containing protein -
PMI20_RS21485 (PMI20_021485) 4818227..4818709 + 483 WP_007930527.1 acyl-CoA thioesterase -
PMI20_RS21490 (PMI20_021490) 4818762..4820411 + 1650 WP_007930525.1 FMN-binding glutamate synthase family protein -
PMI20_RS21495 (PMI20_021495) 4820598..4820879 - 282 WP_007930524.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PMI20_RS21500 (PMI20_021500) 4820869..4821117 - 249 WP_007930518.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PMI20_RS21505 (PMI20_021505) 4821213..4822001 - 789 WP_007930516.1 helix-turn-helix transcriptional regulator -
PMI20_RS21510 (PMI20_021510) 4822086..4823084 + 999 WP_007930514.1 bile acid:sodium symporter family protein -
PMI20_RS21515 (PMI20_021515) 4823238..4824041 - 804 WP_007930512.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4812344..4826123 13779


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10890.73 Da        Isoelectric Point: 10.6993

>T281129 WP_007930524.1 NZ_CP124732:c4820879-4820598 [Pseudomonas sp. GM17]
MTYELEFSEKAWKEWQKLGPTLKEQFKKKLQERLVNPHVPADRLSGLGNAYKIKLRTAGYRLVYRVVDEVLVVTVIAVGK
RERGSVYQQARKR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9011.36 Da        Isoelectric Point: 4.4142

>AT281129 WP_007930518.1 NZ_CP124732:c4821117-4820869 [Pseudomonas sp. GM17]
MTHVLLSNVVASISELKKNPMGTVAAGGGSSVAILNRNEPAFYCVPAKEYEAMMERLEDMELLALCRERENDPTVRVSLD
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H3UB31

Antitoxin

Source ID Structure
AlphaFold DB A0A3G7HDX0

References