Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4297292..4297877 Replicon chromosome
Accession NZ_CP124732
Organism Pseudomonas sp. GM17

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PMI20_RS19325 Protein ID WP_007923532.1
Coordinates 4297292..4297585 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PMI20_RS19330 Protein ID WP_007923531.1
Coordinates 4297587..4297877 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PMI20_RS19305 (PMI20_019305) 4292308..4292703 - 396 WP_007932579.1 carboxymuconolactone decarboxylase family protein -
PMI20_RS19310 (PMI20_019310) 4292935..4294179 - 1245 WP_007923535.1 M20/M25/M40 family metallo-hydrolase -
PMI20_RS19315 (PMI20_019315) 4294273..4295397 - 1125 WP_052034467.1 diguanylate cyclase -
PMI20_RS19320 (PMI20_019320) 4295662..4297056 + 1395 WP_007923533.1 VOC family protein -
PMI20_RS19325 (PMI20_019325) 4297292..4297585 + 294 WP_007923532.1 addiction module protein Toxin
PMI20_RS19330 (PMI20_019330) 4297587..4297877 + 291 WP_007923531.1 putative addiction module antidote protein Antitoxin
PMI20_RS19335 (PMI20_019335) 4298274..4298861 - 588 WP_007923530.1 hypothetical protein -
PMI20_RS19340 (PMI20_019340) 4298985..4300061 - 1077 WP_007923529.1 lipocalin-like domain-containing protein -
PMI20_RS19345 (PMI20_019345) 4300051..4302531 - 2481 WP_037034137.1 FtsX-like permease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-97)

Antitoxin

Uncharacterized protein HI1420

(5-90)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10680.38 Da        Isoelectric Point: 11.1294

>T281127 WP_007923532.1 NZ_CP124732:4297292-4297585 [Pseudomonas sp. GM17]
MDYEILQTTAFARWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSKMRVNMGAGYRISFTLRGNTLIVLLLGGDK
STQPADICQARSLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10227.76 Da        Isoelectric Point: 8.0096

>AT281127 WP_007923531.1 NZ_CP124732:4297587-4297877 [Pseudomonas sp. GM17]
MSDTLLAFDIATLLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVSRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References