Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1999861..2000006 Replicon chromosome
Accession NZ_CP124698
Organism Klebsiella pneumoniae strain KP21317

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1999897..1999999 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1999861..2000006 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJQ33_RS09705 1994991..1997051 + 2061 WP_004151449.1 oligopeptidase B -
QJQ33_RS09710 1997055..1997714 - 660 WP_004180433.1 exodeoxyribonuclease X -
QJQ33_RS09715 1997793..1998023 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QJQ33_RS09720 1998136..1998510 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QJQ33_RS09725 1998514..1999383 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
QJQ33_RS09730 1999400..1999738 + 339 WP_002911404.1 YebY family protein -
- 1999861..2000006 - 146 - - Antitoxin
- 1999897..1999999 + 103 - - Toxin
QJQ33_RS09735 2000375..2000518 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QJQ33_RS09740 2000623..2001591 - 969 WP_004151446.1 VirK/YbjX family protein -
QJQ33_RS09745 2001748..2002401 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QJQ33_RS09750 2002398..2002589 - 192 WP_002911395.1 YebW family protein -
QJQ33_RS09755 2002687..2002926 - 240 WP_002911393.1 YebV family protein -
QJQ33_RS09760 2003042..2004475 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T281088 NZ_CP124698:1999897-1999999 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT281088 NZ_CP124698:c2000006-1999861 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References