Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1903847..1903992 Replicon chromosome
Accession NZ_CP124693
Organism Klebsiella pneumoniae strain KP21300

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1903883..1903985 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1903847..1903992 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJQ26_RS09340 1898977..1901037 + 2061 WP_004151449.1 oligopeptidase B -
QJQ26_RS09345 1901041..1901700 - 660 WP_002911407.1 exodeoxyribonuclease X -
QJQ26_RS09350 1901779..1902009 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QJQ26_RS09355 1902122..1902496 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QJQ26_RS09360 1902500..1903369 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
QJQ26_RS09365 1903386..1903724 + 339 WP_002911404.1 YebY family protein -
- 1903847..1903992 - 146 - - Antitoxin
- 1903883..1903985 + 103 - - Toxin
QJQ26_RS09370 1904360..1904503 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QJQ26_RS09375 1904608..1905576 - 969 WP_004151446.1 VirK/YbjX family protein -
QJQ26_RS09380 1905733..1906386 + 654 WP_032418800.1 protein-serine/threonine phosphatase -
QJQ26_RS09385 1906383..1906574 - 192 WP_002911395.1 YebW family protein -
QJQ26_RS09390 1906672..1906911 - 240 WP_002911393.1 YebV family protein -
QJQ26_RS09395 1907027..1908460 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T281072 NZ_CP124693:1903883-1903985 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT281072 NZ_CP124693:c1903992-1903847 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References