Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 5309636..5310240 Replicon chromosome
Accession NZ_CP124680
Organism Nocardioides sp. L-11A

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QJ852_RS25430 Protein ID WP_282401730.1
Coordinates 5309839..5310240 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QJ852_RS25425 Protein ID WP_282401729.1
Coordinates 5309636..5309845 (+) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJ852_RS25415 (QJ852_25415) 5304801..5306876 - 2076 WP_282401727.1 hypothetical protein -
QJ852_RS25420 (QJ852_25420) 5307072..5309477 - 2406 WP_282401728.1 DEAD/DEAH box helicase -
QJ852_RS25425 (QJ852_25425) 5309636..5309845 + 210 WP_282401729.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QJ852_RS25430 (QJ852_25430) 5309839..5310240 + 402 WP_282401730.1 PIN domain-containing protein Toxin
QJ852_RS25435 (QJ852_25435) 5310698..5312326 - 1629 WP_282401731.1 helix-turn-helix transcriptional regulator -
QJ852_RS25440 (QJ852_25440) 5312449..5313042 + 594 WP_282401732.1 hypothetical protein -
QJ852_RS25445 (QJ852_25445) 5313097..5313678 + 582 WP_282401733.1 hypothetical protein -
QJ852_RS25450 (QJ852_25450) 5313810..5314124 - 315 WP_282401734.1 DUF2470 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-122)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(3-34)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14760.88 Da        Isoelectric Point: 4.8006

>T281067 WP_282401730.1 NZ_CP124680:5309839-5310240 [Nocardioides sp. L-11A]
VVTLVDSSAWIDYFRRPGDPGNEPLRDLIRREEVATSEPIAMELSMGPTDELAVRRIERILGSAVDLSIEADLDFRAAAA
IFRAVRRTGRTVHSTVDCLIAAIAIRHDVPLLHRDADFEAIATVTELRQLSLL

Download         Length: 402 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7963.05 Da        Isoelectric Point: 4.4692

>AT281067 WP_282401729.1 NZ_CP124680:5309636-5309845 [Nocardioides sp. L-11A]
MTRTNIEIDDELIARVMKKYGLRTKREAVDLALRRAAGPKLTPEEILSYEGMGWDGDLDEIRNDPVETW

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References