Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PHD-PIN
Location 2122277..2122947 Replicon chromosome
Accession NZ_CP124680
Organism Nocardioides sp. L-11A

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QJ852_RS10085 Protein ID WP_282404010.1
Coordinates 2122277..2122663 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QJ852_RS10090 Protein ID WP_282404011.1
Coordinates 2122660..2122947 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJ852_RS10055 (QJ852_10055) 2117345..2117749 + 405 WP_282404005.1 DUF2510 domain-containing protein -
QJ852_RS10060 (QJ852_10060) 2117794..2118282 + 489 WP_282404006.1 hypothetical protein -
QJ852_RS10065 (QJ852_10065) 2118269..2119618 - 1350 WP_282404007.1 recombinase family protein -
QJ852_RS10070 (QJ852_10070) 2119640..2120185 + 546 WP_282404641.1 ATP-binding protein -
QJ852_RS10075 (QJ852_10075) 2120182..2121330 + 1149 WP_282404008.1 DNA-processing protein DprA -
QJ852_RS10080 (QJ852_10080) 2121327..2122268 + 942 WP_282404009.1 tyrosine recombinase XerC -
QJ852_RS10085 (QJ852_10085) 2122277..2122663 - 387 WP_282404010.1 type II toxin-antitoxin system VapC family toxin Toxin
QJ852_RS10090 (QJ852_10090) 2122660..2122947 - 288 WP_282404011.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QJ852_RS10095 (QJ852_10095) 2122944..2123549 - 606 WP_282404012.1 M23 family metallopeptidase -
QJ852_RS10100 (QJ852_10100) 2123855..2124754 + 900 WP_282404013.1 30S ribosomal protein S2 -
QJ852_RS10105 (QJ852_10105) 2124797..2125606 + 810 WP_282404014.1 translation elongation factor Ts -
QJ852_RS10110 (QJ852_10110) 2125847..2127067 + 1221 WP_282404015.1 SPFH domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-117)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14024.99 Da        Isoelectric Point: 4.6034

>T281065 WP_282404010.1 NZ_CP124680:c2122663-2122277 [Nocardioides sp. L-11A]
VNVYVDTSAVVKLIAEEAESDALRDYLNGLDPRRVFSSELLVTEVRRAAMRNDVEQSLATEVLESINLFEMTSPLLQHAG
LLPDPTLRSLDAIHLATALRHGAEVLVCYDLRLRTAAERQGLVAASPA

Download         Length: 387 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10919.39 Da        Isoelectric Point: 8.8293

>AT281065 WP_282404011.1 NZ_CP124680:c2122947-2122660 [Nocardioides sp. L-11A]
MSATIVRSGAVERIPHRELRNNSAAILRRVAAGESFEITNHGEVVAILRQPVADDLWYAEMARPATRSRGWNDIERVRAR
RPMQEVLDELREDRL

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References