Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1747491..1748199 Replicon chromosome
Accession NZ_CP124680
Organism Nocardioides sp. L-11A

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QJ852_RS08195 Protein ID WP_282403654.1
Coordinates 1747771..1748199 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QJ852_RS08190 Protein ID WP_282403653.1
Coordinates 1747491..1747784 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJ852_RS08175 (QJ852_08175) 1743425..1744609 + 1185 WP_282403650.1 homogentisate 1,2-dioxygenase -
QJ852_RS08180 (QJ852_08180) 1744613..1745656 - 1044 WP_282403651.1 crosslink repair DNA glycosylase YcaQ family protein -
QJ852_RS08185 (QJ852_08185) 1745676..1747346 - 1671 WP_282403652.1 DUF885 domain-containing protein -
QJ852_RS08190 (QJ852_08190) 1747491..1747784 + 294 WP_282403653.1 CopG family transcriptional regulator Antitoxin
QJ852_RS08195 (QJ852_08195) 1747771..1748199 + 429 WP_282403654.1 PIN domain-containing protein Toxin
QJ852_RS08200 (QJ852_08200) 1748200..1749156 - 957 WP_282403655.1 WYL domain-containing protein -
QJ852_RS08205 (QJ852_08205) 1749211..1750323 + 1113 WP_282403656.1 epoxide hydrolase -
QJ852_RS08210 (QJ852_08210) 1750359..1751069 - 711 WP_282403657.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-134)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15834.89 Da        Isoelectric Point: 5.9654

>T281064 WP_282403654.1 NZ_CP124680:1747771-1748199 [Nocardioides sp. L-11A]
MNVLDVNVVIPLYRGDHSHHAAATAWWQQSVTAGETFTVPDLVWVGFVRMITNRRVFPEPSAFRDAWEFAAALMAQPTYT
TWTAHPRTLEEFTALSAQAGARADLVTDAYIAACAATYGGTVVTFDRDFRKFDGLRVHELTL

Download         Length: 429 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10330.53 Da        Isoelectric Point: 4.6364

>AT281064 WP_282403653.1 NZ_CP124680:1747491-1747784 [Nocardioides sp. L-11A]
VRTTVNIHDGLLATVKHRAQEEGKTLGDVFEDALRSYLLADRTEEVTEAAPPSLPVFRGGTGLAPGIDPSSNASLYEAMY
AAEDAALAALIRGHERP

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References