Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1564829..1565460 Replicon chromosome
Accession NZ_CP124680
Organism Nocardioides sp. L-11A

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QJ852_RS07345 Protein ID WP_282403487.1
Coordinates 1564829..1565230 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QJ852_RS07350 Protein ID WP_282403488.1
Coordinates 1565227..1565460 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJ852_RS07320 (QJ852_07320) 1560412..1561458 - 1047 WP_282403482.1 hypothetical protein -
QJ852_RS07325 (QJ852_07325) 1561458..1561970 - 513 WP_282403483.1 hypothetical protein -
QJ852_RS07330 (QJ852_07330) 1561954..1562865 - 912 WP_282403484.1 DUF58 domain-containing protein -
QJ852_RS07335 (QJ852_07335) 1562873..1563931 - 1059 WP_282403485.1 MoxR family ATPase -
QJ852_RS07340 (QJ852_07340) 1563993..1564799 - 807 WP_282403486.1 RDD family protein -
QJ852_RS07345 (QJ852_07345) 1564829..1565230 - 402 WP_282403487.1 PIN domain-containing protein Toxin
QJ852_RS07350 (QJ852_07350) 1565227..1565460 - 234 WP_282403488.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QJ852_RS07355 (QJ852_07355) 1565549..1566553 + 1005 WP_282403489.1 stage II sporulation protein M -
QJ852_RS07360 (QJ852_07360) 1566586..1567941 + 1356 WP_282403490.1 FAD-dependent oxidoreductase -
QJ852_RS07365 (QJ852_07365) 1568010..1568723 + 714 WP_282403491.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-127)

Antitoxin

SpoVT-AbrB domain

(9-46)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14741.72 Da        Isoelectric Point: 7.4070

>T281063 WP_282403487.1 NZ_CP124680:c1565230-1564829 [Nocardioides sp. L-11A]
MNPRHRHLLDTDVAIELLRKRDVALREAWRAAGRVAASSVSLFELRFGAARSAEPARNDLAVDELAAAVDFLDFDAEAAA
HAGDIRADLARLGTPIGAYDVMIAGHARSRGLIVVTRNEREFRRVDGLRVERW

Download         Length: 402 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8578.64 Da        Isoelectric Point: 4.7085

>AT281063 WP_282403488.1 NZ_CP124680:c1565460-1565227 [Nocardioides sp. L-11A]
MSVVTRLFLSNRTQAVRLPKAVAFDASVSEVEIDIVGDARVIRPAGSRVDAFWSSDMRVSDDFAREQPEAPQERAWA

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References