Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/- |
Location | 3594669..3595889 | Replicon | chromosome |
Accession | NZ_CP124666 | ||
Organism | Pseudomonas aeruginosa strain 2021CK-01283 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | A0A0H2Z8V4 |
Locus tag | QJ983_RS16690 | Protein ID | WP_003110488.1 |
Coordinates | 3595311..3595889 (+) | Length | 193 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | QJ983_RS16685 | Protein ID | WP_003132728.1 |
Coordinates | 3594669..3595223 (+) | Length | 185 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QJ983_RS16660 (QJ983_16660) | 3590237..3590788 | + | 552 | WP_031685890.1 | XRE family transcriptional regulator | - |
QJ983_RS16665 (QJ983_16665) | 3590785..3591183 | - | 399 | WP_003088123.1 | NADH-quinone oxidoreductase subunit A | - |
QJ983_RS16670 (QJ983_16670) | 3591196..3591519 | - | 324 | WP_003102734.1 | multidrug efflux SMR transporter | - |
QJ983_RS16675 (QJ983_16675) | 3591850..3592311 | + | 462 | WP_003102736.1 | (2Fe-2S)-binding protein | - |
QJ983_RS16680 (QJ983_16680) | 3592316..3594511 | + | 2196 | WP_033957494.1 | xanthine dehydrogenase family protein molybdopterin-binding subunit | - |
QJ983_RS16685 (QJ983_16685) | 3594669..3595223 | + | 555 | WP_003132728.1 | helix-turn-helix transcriptional regulator | Antitoxin |
QJ983_RS16690 (QJ983_16690) | 3595311..3595889 | + | 579 | WP_003110488.1 | HD domain-containing protein | Toxin |
QJ983_RS16695 (QJ983_16695) | 3595999..3597186 | - | 1188 | WP_003110489.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
QJ983_RS16700 (QJ983_16700) | 3597176..3599347 | - | 2172 | WP_033957491.1 | type I secretion system permease/ATPase | - |
QJ983_RS16705 (QJ983_16705) | 3599337..3600614 | - | 1278 | WP_003088104.1 | TolC family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 193 a.a. Molecular weight: 21913.75 Da Isoelectric Point: 5.3655
>T281035 WP_003110488.1 NZ_CP124666:3595311-3595889 [Pseudomonas aeruginosa]
MSLELLSNRLEFLREAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDTPLRDRLLALWDEYERGETAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKTLRELLDARTRQRLAARRDA
MSLELLSNRLEFLREAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDTPLRDRLLALWDEYERGETAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKTLRELLDARTRQRLAARRDA
Download Length: 579 bp
Antitoxin
Download Length: 185 a.a. Molecular weight: 20470.63 Da Isoelectric Point: 8.1590
>AT281035 WP_003132728.1 NZ_CP124666:3594669-3595223 [Pseudomonas aeruginosa]
MTEPLPSSSLGPALRRWRLLHRVKQTHAAELLGVAQSTISRWESGTQALLVEERARLERLLGARLESAADQALARLVEAN
PQPVHLICDLTHRLLACSPARAAQFGVPLGELLDRSLWPYCSEEILRQEATLEELGWRELLAPPALEFASGANASAIVPI
RRSRCRWTRMTLSDGRAVRLVETL
MTEPLPSSSLGPALRRWRLLHRVKQTHAAELLGVAQSTISRWESGTQALLVEERARLERLLGARLESAADQALARLVEAN
PQPVHLICDLTHRLLACSPARAAQFGVPLGELLDRSLWPYCSEEILRQEATLEELGWRELLAPPALEFASGANASAIVPI
RRSRCRWTRMTLSDGRAVRLVETL
Download Length: 555 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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