Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 1911611..1913119 Replicon chromosome
Accession NZ_CP124666
Organism Pseudomonas aeruginosa strain 2021CK-01283

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag QJ983_RS09005 Protein ID WP_023443480.1
Coordinates 1911611..1912198 (+) Length 196 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag QJ983_RS09010 Protein ID WP_031685565.1
Coordinates 1912265..1913119 (+) Length 285 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJ983_RS09000 (QJ983_09000) 1907866..1911345 - 3480 WP_003117605.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -
QJ983_RS09005 (QJ983_09005) 1911611..1912198 + 588 WP_023443480.1 GNAT family protein Toxin
QJ983_RS09010 (QJ983_09010) 1912265..1913119 + 855 WP_031685565.1 AraC family transcriptional regulator Antitoxin
QJ983_RS09015 (QJ983_09015) 1913216..1915381 + 2166 WP_003091606.1 TonB-dependent receptor family protein -
QJ983_RS09020 (QJ983_09020) 1915556..1917430 + 1875 WP_003091605.1 MFS transporter -
QJ983_RS09025 (QJ983_09025) 1917491..1917700 - 210 WP_003091604.1 cold-shock protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(20-152)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(19-151)


Sequences

Toxin        


Download         Length: 196 a.a.        Molecular weight: 21931.26 Da        Isoelectric Point: 9.8676

>T281034 WP_023443480.1 NZ_CP124666:1911611-1912198 [Pseudomonas aeruginosa]
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRTLPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG

Download         Length: 588 bp

Antitoxin


Download         Length: 285 a.a.        Molecular weight: 31819.13 Da        Isoelectric Point: 7.8141

>AT281034 WP_031685565.1 NZ_CP124666:1912265-1913119 [Pseudomonas aeruginosa]
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHAGSLETQTRWRETVLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLAPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTTYE

Download         Length: 855 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References