Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RHH(antitoxin) |
Location | 150698..151203 | Replicon | chromosome |
Accession | NZ_CP124658 | ||
Organism | Pseudomonas aeruginosa strain 2022CK-00068 |
Toxin (Protein)
Gene name | parE | Uniprot ID | V6A7K8 |
Locus tag | P7I93_RS00685 | Protein ID | WP_003083773.1 |
Coordinates | 150698..150979 (-) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | A0A1C7BDS9 |
Locus tag | P7I93_RS00690 | Protein ID | WP_003083775.1 |
Coordinates | 150976..151203 (-) | Length | 76 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
P7I93_RS00660 (P7I93_00660) | 145949..147298 | + | 1350 | WP_003137006.1 | C4-dicarboxylate transporter DctA | - |
P7I93_RS00665 (P7I93_00665) | 147347..148033 | + | 687 | WP_003083762.1 | FadR/GntR family transcriptional regulator | - |
P7I93_RS00670 (P7I93_00670) | 148134..148868 | + | 735 | WP_003083764.1 | GntR family transcriptional regulator | - |
P7I93_RS00675 (P7I93_00675) | 149048..149458 | + | 411 | WP_003110659.1 | aegerolysin family protein | - |
P7I93_RS00680 (P7I93_00680) | 149490..150398 | - | 909 | WP_003083769.1 | LysR family transcriptional regulator | - |
P7I93_RS00685 (P7I93_00685) | 150698..150979 | - | 282 | WP_003083773.1 | type II toxin-antitoxin system toxin ParE | Toxin |
P7I93_RS00690 (P7I93_00690) | 150976..151203 | - | 228 | WP_003083775.1 | CopG family ribbon-helix-helix protein | Antitoxin |
P7I93_RS00695 (P7I93_00695) | 151379..151999 | - | 621 | WP_023092259.1 | hypothetical protein | - |
P7I93_RS00700 (P7I93_00700) | 152100..152600 | + | 501 | WP_003101228.1 | LEA type 2 family protein | - |
P7I93_RS00705 (P7I93_00705) | 152673..153014 | + | 342 | WP_003101229.1 | zinc ribbon domain-containing protein YjdM | - |
P7I93_RS00710 (P7I93_00710) | 153096..154523 | - | 1428 | WP_023092260.1 | GABA permease | - |
P7I93_RS00715 (P7I93_00715) | 154692..156185 | - | 1494 | WP_003101230.1 | CoA-acylating methylmalonate-semialdehyde dehydrogenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10462.19 Da Isoelectric Point: 10.0435
>T280988 WP_003083773.1 NZ_CP124658:c150979-150698 [Pseudomonas aeruginosa]
MSLKWTRKAAADLDAIYDHYVVLIGPEKALKAVQDIVEQVKPLQQVANQGAGRPSEVPGVRTLTLERWPFSAPFRVKGKE
IQILRIDRVEITP
MSLKWTRKAAADLDAIYDHYVVLIGPEKALKAVQDIVEQVKPLQQVANQGAGRPSEVPGVRTLTLERWPFSAPFRVKGKE
IQILRIDRVEITP
Download Length: 282 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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