Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 280320..281275 Replicon chromosome
Accession NZ_CP124646
Organism Pseudomonas aeruginosa strain 2020CK-00185

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag P7I78_RS01295 Protein ID WP_170868735.1
Coordinates 280949..281275 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag P7I78_RS01290 Protein ID WP_023107584.1
Coordinates 280320..280877 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P7I78_RS01265 (P7I78_01265) 275377..275664 - 288 WP_003137130.1 hypothetical protein -
P7I78_RS01270 (P7I78_01270) 275756..276232 - 477 WP_003118626.1 MarR family transcriptional regulator -
P7I78_RS01275 (P7I78_01275) 276273..277763 - 1491 WP_003137133.1 UbiD family decarboxylase HudA -
P7I78_RS01280 (P7I78_01280) 277897..278583 - 687 WP_003106170.1 YoaK family protein -
P7I78_RS01285 (P7I78_01285) 278747..279679 - 933 WP_003084116.1 hypothetical protein -
P7I78_RS01290 (P7I78_01290) 280320..280877 + 558 WP_023107584.1 Panacea domain-containing protein Antitoxin
P7I78_RS01295 (P7I78_01295) 280949..281275 + 327 WP_170868735.1 hypothetical protein Toxin
P7I78_RS01305 (P7I78_01305) 282717..284309 - 1593 WP_277424738.1 DUF2875 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(28-138)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12385.38 Da        Isoelectric Point: 9.1081

>T280928 WP_170868735.1 NZ_CP124646:280949-281275 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLRDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Download         Length: 327 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 21377.14 Da        Isoelectric Point: 5.8950

>AT280928 WP_023107584.1 NZ_CP124646:280320-280877 [Pseudomonas aeruginosa]
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References