280919

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 6091075..6091659 Replicon chromosome
Accession NZ_CP124638
Organism Pseudomonas aeruginosa strain 2021CK-01158

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P7I84_RS28480 Protein ID WP_033996895.1
Coordinates 6091369..6091659 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P7I84_RS28475 Protein ID WP_033996897.1
Coordinates 6091075..6091368 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P7I84_RS28445 (P7I84_28455) 6086425..6086658 + 234 WP_033996905.1 hypothetical protein -
P7I84_RS28450 (P7I84_28460) 6086678..6089395 + 2718 WP_033996995.1 toprim domain-containing protein -
P7I84_RS28455 (P7I84_28465) 6089440..6089583 + 144 WP_153576040.1 hypothetical protein -
P7I84_RS28460 (P7I84_28470) 6089634..6090209 + 576 WP_052157654.1 hypothetical protein -
P7I84_RS28465 (P7I84_28475) 6090401..6090571 + 171 WP_108242490.1 antitoxin -
P7I84_RS28470 (P7I84_28480) 6090568..6090960 + 393 WP_033996900.1 hypothetical protein -
P7I84_RS28475 (P7I84_28485) 6091075..6091368 - 294 WP_033996897.1 putative addiction module antidote protein Antitoxin
P7I84_RS28480 (P7I84_28490) 6091369..6091659 - 291 WP_033996895.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P7I84_RS28485 (P7I84_28495) 6091970..6092170 + 201 WP_033996893.1 hypothetical protein -
P7I84_RS28490 (P7I84_28500) 6092170..6092394 + 225 WP_033996891.1 hypothetical protein -
P7I84_RS28495 (P7I84_28505) 6092403..6092945 + 543 WP_161566247.1 phage antirepressor N-terminal domain-containing protein -
P7I84_RS28500 (P7I84_28510) 6092965..6093162 + 198 WP_033996889.1 hypothetical protein -
P7I84_RS28505 (P7I84_28515) 6093241..6093450 + 210 WP_033996886.1 hypothetical protein -
P7I84_RS28510 (P7I84_28520) 6093447..6094589 + 1143 WP_033996883.1 integrase -
P7I84_RS28515 (P7I84_28525) 6094988..6096046 + 1059 WP_003096179.1 dTDP-glucose 4,6-dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 6020779..6096046 75267


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(8-94)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11001.67 Da        Isoelectric Point: 6.3329

>T280919 WP_033996895.1 NZ_CP124638:c6091659-6091369 [Pseudomonas aeruginosa]
MYSIIETEAFSDWLNGLKDTVTRMRLIKRLQRASLGNLGDVKPVGEGVYEMREFFGPGWRMYYVQQGDVLLIMLGGGDKS
SQQRDIERAIQLSKEL

Download         Length: 291 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10648.27 Da        Isoelectric Point: 6.4678

>AT280919 WP_033996897.1 NZ_CP124638:c6091368-6091075 [Pseudomonas aeruginosa]
MNKTKLNMRPFDAAHYLNNEEEMAAYLDVILEDNDPALLAVALGDIARARGMTELARKTGLSRESLYKSLSGERVPSTET
LLKVIHALGFKLTVSAA

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References