Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 1021578..1023244 Replicon chromosome
Accession NZ_CP124614
Organism Vibrio sp. YMD68

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag QF117_RS10895 Protein ID WP_282388953.1
Coordinates 1022042..1023244 (+) Length 401 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag QF117_RS10890 Protein ID WP_282388952.1
Coordinates 1021578..1022045 (+) Length 156 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QF117_RS10885 (QF117_10885) 1019527..1021419 + 1893 WP_282388951.1 hypothetical protein -
QF117_RS10890 (QF117_10890) 1021578..1022045 + 468 WP_282388952.1 DUF4065 domain-containing protein Antitoxin
QF117_RS10895 (QF117_10895) 1022042..1023244 + 1203 WP_282388953.1 RelA/SpoT domain-containing protein Toxin
QF117_RS10900 (QF117_10900) 1023300..1024178 - 879 WP_282388954.1 hypothetical protein -
QF117_RS10905 (QF117_10905) 1024198..1024809 - 612 WP_282388955.1 hypothetical protein -
QF117_RS10910 (QF117_10910) 1024890..1025135 - 246 WP_282387847.1 hypothetical protein -
QF117_RS10915 (QF117_10915) 1025247..1025741 - 495 WP_282387848.1 DUF2787 domain-containing protein -
QF117_RS10920 (QF117_10920) 1025850..1026545 - 696 WP_282387849.1 hypothetical protein -
QF117_RS10925 (QF117_10925) 1026627..1027061 - 435 WP_282387850.1 DUF2787 family protein -
QF117_RS10930 (QF117_10930) 1027061..1027540 - 480 WP_282388956.1 DNA repair protein RadC -
QF117_RS10935 (QF117_10935) 1027769..1028125 - 357 WP_282388957.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(111-228)

Antitoxin

(32-123)


Sequences


Toxin        


Download         Length: 401 a.a.        Molecular weight: 45177.09 Da        Isoelectric Point: 5.6754

>T280878 WP_282388953.1 NZ_CP124614:1022042-1023244 [Vibrio sp. YMD68]
VSDKEKSVVSFLIDDTPSAEQSSKTFHDDYELNFQDFLERTVDERAAEDFSYTNNGVKKAGRRLRKKEGDLKSATTTIQQ
FRAAHEKPLNTIAYLVGRCCRELGIDVKPVTRLKRLDTIIDKLQRKSLDGHTANATCVTNMNDIGGCRAIFPDLISLEQA
VSQLQGTVEKVGRVRIKDIDNYISNPKPNDCGYRSLHVIYRYDHTSGKSFNIEAQLRTRLQHLWATTVEIVDILEGTKIK
THSHSANEDKDDLQIKWEELLSIMSRYIADAEGAIVLGEEEINQCSIRLRELNDEINALGRLKTFRILSEKIETCCDDAT
EHVLLIIDEKSLKLIFSEEFSDYSKAISVYNAAEKVTSSHSGINALLISTKNMGQLSEAYPNYLGDCASFIVLLQEAMQR

Download         Length: 1203 bp


Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17436.82 Da        Isoelectric Point: 7.2983

>AT280878 WP_282388952.1 NZ_CP124614:1021578-1022045 [Vibrio sp. YMD68]
MKTYHTYNAVDVALSLLKHAKEQGKCFSNLQLQKLTYVCHGLSLAHFQRPLVVDDVFAWKFGPVVPSVYFRFKSYGSNVI
TEHGDVVLDAESESIVKDVVSKLGDLSGPQLVDLTHRDGSPWHQVWDGTHQKVIPDHLIQSHYVQIKQSGHTTSL

Download         Length: 468 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References