Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 567560..568323 Replicon chromosome
Accession NZ_CP124614
Organism Vibrio sp. YMD68

Toxin (Protein)


Gene name ataT Uniprot ID A0A919BFZ0
Locus tag QF117_RS08645 Protein ID WP_023584043.1
Coordinates 567560..568066 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag QF117_RS08650 Protein ID WP_000212004.1
Coordinates 568057..568323 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QF117_RS08615 (QF117_08615) 563413..563694 + 282 WP_000433891.1 type IV conjugative transfer system protein TraL -
QF117_RS08620 (QF117_08620) 563691..564317 + 627 WP_000667170.1 TraE/TraK family type IV conjugative transfer system protein -
QF117_RS08625 (QF117_08625) 564301..565197 + 897 WP_269123861.1 type-F conjugative transfer system secretin TraK -
QF117_RS08630 (QF117_08630) 565200..566489 + 1290 WP_169650375.1 TraB/VirB10 family protein -
QF117_RS08635 (QF117_08635) 566564..567136 + 573 WP_001944091.1 type IV conjugative transfer system lipoprotein TraV -
QF117_RS08640 (QF117_08640) 567133..567519 + 387 WP_023584042.1 TraA family conjugative transfer protein -
QF117_RS08645 (QF117_08645) 567560..568066 - 507 WP_023584043.1 GNAT family N-acetyltransferase Toxin
QF117_RS08650 (QF117_08650) 568057..568323 - 267 WP_000212004.1 DUF1778 domain-containing protein Antitoxin
QF117_RS08655 (QF117_08655) 568692..569384 + 693 WP_001228924.1 DsbC family protein -
QF117_RS08660 (QF117_08660) 569384..571783 + 2400 WP_024008831.1 type IV secretion system protein TraC -
QF117_RS08665 (QF117_08665) 571776..572123 + 348 WP_004249366.1 hypothetical protein -
QF117_RS08670 (QF117_08670) 572107..572619 + 513 WP_172665238.1 S26 family signal peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-146)

Antitoxin

Vibrio phage ICP1, Orf50

(8-83)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18278.00 Da        Isoelectric Point: 7.2132

>T280876 WP_023584043.1 NZ_CP124614:c568066-567560 [Vibrio sp. YMD68]
MGISAPTLLTDEHQLNAFQCGIEELDTWLRKQALKSQKRGTARVYVVNDTDAHQVVGYYAIAMGSVSREQAFSSLRRNSP
DPIPMVILARLGVDNAYQGQGIAAGLLKDCIIRSVQAMNAVGGAGILVHAIDGSAQTFYKKFGFKESTFDPLVLMARICD
IEKSLSID

Download         Length: 507 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9956.48 Da        Isoelectric Point: 5.8580

>AT280876 WP_000212004.1 NZ_CP124614:c568323-568057 [Vibrio sp. YMD68]
MATKTAPINMRVLPSVRDIIDAAASLKKVDRTVFIQQAALNEAHSILAEQRDFVLEAKAFEAFDNELRAEPQTLEGMKDL
FKRKAPWE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References