Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 945912..946440 Replicon chromosome
Accession NZ_CP124613
Organism Vibrio sp. YMD68

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QF117_RS04265 Protein ID WP_282384863.1
Coordinates 945912..946202 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A347UR02
Locus tag QF117_RS04270 Protein ID WP_005377003.1
Coordinates 946192..946440 (-) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QF117_RS04245 (QF117_04245) 941493..942443 + 951 WP_102386837.1 DUF559 domain-containing protein -
QF117_RS04250 (QF117_04250) 942464..942556 + 93 WP_005445235.1 DUF3265 domain-containing protein -
QF117_RS04255 (QF117_04255) 942590..942910 + 321 WP_282384861.1 hypothetical protein -
QF117_RS04260 (QF117_04260) 942900..943391 + 492 WP_108162637.1 hypothetical protein -
QF117_RS04265 (QF117_04265) 945912..946202 - 291 WP_282384863.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QF117_RS04270 (QF117_04270) 946192..946440 - 249 WP_005377003.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QF117_RS04275 (QF117_04275) 947254..947550 - 297 WP_282384864.1 type II toxin-antitoxin system RelE/ParE family toxin -
QF117_RS04280 (QF117_04280) 947557..947799 - 243 WP_045957228.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
QF117_RS04285 (QF117_04285) 948081..948587 + 507 WP_282384803.1 hypothetical protein -
QF117_RS04290 (QF117_04290) 948610..948702 + 93 WP_079764003.1 DUF3265 domain-containing protein -
QF117_RS04295 (QF117_04295) 948714..950303 + 1590 WP_282384871.1 RNA-directed DNA polymerase -
QF117_RS04300 (QF117_04300) 950260..951372 + 1113 WP_282384872.1 DUF2971 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 894306..961154 66848
- inside Genomic island - - 928286..952694 24408


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 11218.22 Da        Isoelectric Point: 10.5021

>T280873 WP_282384863.1 NZ_CP124613:c946202-945912 [Vibrio sp. YMD68]
MTYKLDFKKSALKEWKKLGSTLQQQFKKKLIERLDNPHVPASKLSGADNMYKIKLRQSGYRLVYKVEDDVIIVTVLAVGK
RERSDVYLKAMKRLDD

Download         Length: 291 bp


Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9079.37 Da        Isoelectric Point: 3.9610

>AT280873 WP_005377003.1 NZ_CP124613:c946440-946192 [Vibrio sp. YMD68]
MTTRILADVAASITELKANPMKVATSAYGEPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLAIAKERESEESISVNID
DL

Download         Length: 249 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A347UR02

References