Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 917478..918016 Replicon chromosome
Accession NZ_CP124613
Organism Vibrio sp. YMD68

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag QF117_RS04110 Protein ID WP_170908050.1
Coordinates 917478..917777 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag QF117_RS04115 Protein ID WP_282384828.1
Coordinates 917774..918016 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QF117_RS04090 (QF117_04090) 913643..914539 + 897 WP_282384822.1 hypothetical protein -
QF117_RS04095 (QF117_04095) 914662..914970 + 309 WP_282384824.1 DUF2834 domain-containing protein -
QF117_RS04100 (QF117_04100) 915439..915981 + 543 WP_282384826.1 DinB family protein -
QF117_RS04105 (QF117_04105) 917001..917366 + 366 WP_282384827.1 hypothetical protein -
QF117_RS04110 (QF117_04110) 917478..917777 - 300 WP_170908050.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QF117_RS04115 (QF117_04115) 917774..918016 - 243 WP_282384828.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
QF117_RS04120 (QF117_04120) 919309..919842 + 534 WP_282384830.1 J domain-containing protein -
QF117_RS04125 (QF117_04125) 920483..920821 + 339 WP_282384832.1 DUF6404 family protein -
QF117_RS04130 (QF117_04130) 921294..921890 + 597 WP_282384833.1 class I SAM-dependent methyltransferase -
QF117_RS04135 (QF117_04135) 922024..922365 + 342 WP_213867509.1 SH3 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 894306..961154 66848
- inside Genomic island - - 892770..912997 20227


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11691.38 Da        Isoelectric Point: 9.9225

>T280872 WP_170908050.1 NZ_CP124613:c917777-917478 [Vibrio sp. YMD68]
MKPFQLTNKAKTDLRDIALFTSRRWGREQRNIYLKQFDDSFWLLAENPDIGKTCDEIRDGYRKFPQGSHVIFYRQVGSQN
IEVIRILHKSMDVNPIFGA

Download         Length: 300 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8898.80 Da        Isoelectric Point: 4.2213

>AT280872 WP_282384828.1 NZ_CP124613:c918016-917774 [Vibrio sp. YMD68]
MAKNTSITLGDHFDGFIAGQIQSGRYGSASEVIRSALRLLETQETKMNTLRQLLVEGEESGTADYDLDSFINELDSEERK

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References