Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 895538..896087 Replicon chromosome
Accession NZ_CP124613
Organism Vibrio sp. YMD68

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag QF117_RS04000 Protein ID WP_282384797.1
Coordinates 895538..895837 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag QF117_RS04005 Protein ID WP_282384798.1
Coordinates 895845..896087 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QF117_RS03985 (QF117_03985) 891484..892623 - 1140 WP_282384794.1 hypothetical protein -
QF117_RS03990 (QF117_03990) 892770..894059 - 1290 WP_282384795.1 hypothetical protein -
QF117_RS03995 (QF117_03995) 894306..895271 - 966 WP_282386147.1 integron integrase -
QF117_RS04000 (QF117_04000) 895538..895837 - 300 WP_282384797.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QF117_RS04005 (QF117_04005) 895845..896087 - 243 WP_282384798.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QF117_RS04010 (QF117_04010) 897377..897703 + 327 WP_282384799.1 hypothetical protein -
QF117_RS04015 (QF117_04015) 898727..899215 + 489 WP_282384801.1 hypothetical protein -
QF117_RS04020 (QF117_04020) 899764..900270 + 507 WP_282384803.1 hypothetical protein -
QF117_RS04025 (QF117_04025) 900293..900385 + 93 WP_079764003.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 894306..961154 66848
- inside Genomic island - - 892770..912997 20227


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-49)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11421.10 Da        Isoelectric Point: 9.3362

>T280871 WP_282384797.1 NZ_CP124613:c895837-895538 [Vibrio sp. YMD68]
MHQSKYKLSKLAQTHLHKIKNYTVINFSEMQWNAYKDTLITGFQMLADNPSVGRSCNDLYENGVYFPIGKHTAYFTKEDG
FILIVAILGQSQLPQNHLR

Download         Length: 300 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8994.20 Da        Isoelectric Point: 4.7672

>AT280871 WP_282384798.1 NZ_CP124613:c896087-895845 [Vibrio sp. YMD68]
MYTLTANDAKRNFGELLLNAQREPVKISKNNKDAVVVMSIRDYEELEAMKADYIKHCFESAKADLAQGNVVDGENFLNAL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References