Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 3115700..3116145 Replicon chromosome
Accession NZ_CP124576
Organism Sphingobium sp. AP49

Toxin (Protein)


Gene name relE Uniprot ID J2DR07
Locus tag PMI04_RS14845 Protein ID WP_007706483.1
Coordinates 3115867..3116145 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PMI04_RS14840 Protein ID WP_010336649.1
Coordinates 3115700..3115870 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PMI04_RS14825 (PMI04_014825) 3111206..3114133 + 2928 WP_007706495.1 excinuclease ABC subunit UvrA -
PMI04_RS14830 (PMI04_014830) 3114157..3114996 + 840 WP_007706491.1 hypothetical protein -
PMI04_RS14835 (PMI04_014835) 3114998..3115504 + 507 WP_157178083.1 hypothetical protein -
PMI04_RS14840 (PMI04_014840) 3115700..3115870 + 171 WP_010336649.1 hypothetical protein Antitoxin
PMI04_RS14845 (PMI04_014845) 3115867..3116145 + 279 WP_007706483.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PMI04_RS14850 (PMI04_014850) 3116434..3117597 + 1164 WP_007706482.1 hypothetical protein -
PMI04_RS14855 (PMI04_014855) 3117766..3117981 + 216 WP_007706481.1 cold-shock protein -
PMI04_RS14860 (PMI04_014860) 3118079..3118282 + 204 WP_007706479.1 hypothetical protein -
PMI04_RS14865 (PMI04_014865) 3118279..3118914 - 636 WP_007706477.1 hypothetical protein -
PMI04_RS14870 (PMI04_014870) 3119193..3119633 + 441 WP_007706474.1 hypothetical protein -
PMI04_RS14875 (PMI04_014875) 3119774..3119974 + 201 WP_007706470.1 hypothetical protein -
PMI04_RS14880 (PMI04_014880) 3120154..3120525 + 372 WP_007706468.1 glycine zipper 2TM domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10451.99 Da        Isoelectric Point: 6.9870

>T280860 WP_007706483.1 NZ_CP124576:3115867-3116145 [Sphingobium sp. AP49]
MTLPVVWDDEAETALLTILDYIGPRNKLAADRLYAAIRHTADNLPNHPYAHRPGRTPGTREAVVHPNYILIYRVAIEAIE
ILTLVHARQQYP

Download         Length: 279 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6238.14 Da        Isoelectric Point: 7.2019

>AT280860 WP_010336649.1 NZ_CP124576:3115700-3115870 [Sphingobium sp. AP49]
MTKLTPIESEFATTEDAEAHDAWVRAKVERALASTKPRIPHDAVMAKAQAVLDKYK

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB J2DR07

Antitoxin

Source ID Structure

References