Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF-MazE
Location 6406624..6407201 Replicon chromosome
Accession NZ_CP124543
Organism Halotia branconii CENA392

Toxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QI031_RS28060 Protein ID WP_281482840.1
Coordinates 6406624..6406947 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QI031_RS28065 Protein ID WP_281482841.1
Coordinates 6406941..6407201 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QI031_RS28045 (QI031_28045) 6402602..6403030 - 429 WP_281482837.1 hypothetical protein -
QI031_RS28050 (QI031_28050) 6403554..6404816 + 1263 WP_281482838.1 hypothetical protein -
QI031_RS28055 (QI031_28055) 6405180..6405854 - 675 WP_281482839.1 hypothetical protein -
QI031_RS28060 (QI031_28060) 6406624..6406947 - 324 WP_281482840.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QI031_RS28065 (QI031_28065) 6406941..6407201 - 261 WP_281482841.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QI031_RS28070 (QI031_28070) 6407473..6408495 + 1023 WP_281482842.1 saccharopine dehydrogenase-like oxidoreductase -
QI031_RS28075 (QI031_28075) 6408564..6408941 - 378 WP_281482843.1 four helix bundle protein -
QI031_RS28080 (QI031_28080) 6408978..6409535 - 558 WP_281486144.1 hypothetical protein -
QI031_RS28085 (QI031_28085) 6409608..6410831 - 1224 WP_281482844.1 type II secretion system F family protein -
QI031_RS28090 (QI031_28090) 6411030..6412154 - 1125 WP_281482845.1 type IV pilus twitching motility protein PilT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-104)

Antitoxin

SpoVT-AbrB domain

(10-47)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12061.08 Da        Isoelectric Point: 6.2755

>T280851 WP_281482840.1 NZ_CP124543:c6406947-6406624 [Halotia branconii CENA392]
MVVKRFDVFLVNLDPTIGSEIQKTRPCVVISPDEMNRYIATVIVAPMTTKGQVYPTRIACQFQGKDGQIVLDQIRTVDKA
RLIKQLGQISDYEQKAVLDTLAEMFAE

Download         Length: 324 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9711.01 Da        Isoelectric Point: 4.6340

>AT280851 WP_281482841.1 NZ_CP124543:c6407201-6406941 [Halotia branconii CENA392]
MGAVIKTRIVKIGNSQGVRIPKPLLEQSGIHTEVEIEVHGNHLIVRAAPKLRVGWEEAFAAMAEQHDDVLLDDVSSTDWD
QLEWEW

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References