Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 5512422..5512984 Replicon chromosome
Accession NZ_CP124543
Organism Halotia branconii CENA392

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QI031_RS24205 Protein ID WP_281482148.1
Coordinates 5512643..5512984 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QI031_RS24200 Protein ID WP_281482147.1
Coordinates 5512422..5512646 (+) Length 75 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QI031_RS24175 (QI031_24175) 5508421..5508915 + 495 WP_281482142.1 hypothetical protein -
QI031_RS24180 (QI031_24180) 5509344..5510039 + 696 WP_281482143.1 pentapeptide repeat-containing protein -
QI031_RS24185 (QI031_24185) 5510159..5510983 + 825 WP_281482144.1 SDR family oxidoreductase -
QI031_RS24190 (QI031_24190) 5511006..5511902 + 897 WP_281482145.1 alpha/beta hydrolase -
QI031_RS24195 (QI031_24195) 5511909..5512250 - 342 WP_281482146.1 thioredoxin -
QI031_RS24200 (QI031_24200) 5512422..5512646 + 225 WP_281482147.1 DUF433 domain-containing protein Antitoxin
QI031_RS24205 (QI031_24205) 5512643..5512984 + 342 WP_281482148.1 DUF5615 family PIN-like protein Toxin
QI031_RS24210 (QI031_24210) 5513073..5513750 + 678 WP_281482149.1 polysaccharide deacetylase family protein -
QI031_RS24215 (QI031_24215) 5514470..5517262 - 2793 WP_281482150.1 preprotein translocase subunit SecA -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-79)

Antitoxin

(8-63)


Sequences


Toxin        


Download         Length: 114 a.a.        Molecular weight: 12312.14 Da        Isoelectric Point: 4.1232

>T280846 WP_281482148.1 NZ_CP124543:5512643-5512984 [Halotia branconii CENA392]
MTTIWIDVHLSPAIASWITNTFGVTAIALRDLGLRDAEDPKIFEAAKAERAIFMTKDSDFVDLVDRLGVPPQIIWLTCGN
TSNARLQEILASTLLEALALLSTGEQLVEISGD

Download         Length: 342 bp


Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8190.57 Da        Isoelectric Point: 5.0019

>AT280846 WP_281482147.1 NZ_CP124543:5512422-5512646 [Halotia branconii CENA392]
MSNLLERITVNPKQCGGRPCIRGMRIRVSDVLDLFAAGLSAEEILEDLPDLEMDDIRASLVYAARKLNHPVLVA

Download         Length: 225 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References