Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 4389019..4389555 Replicon chromosome
Accession NZ_CP124543
Organism Halotia branconii CENA392

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag QI031_RS19320 Protein ID WP_281481276.1
Coordinates 4389019..4389318 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag QI031_RS19325 Protein ID WP_281481277.1
Coordinates 4389322..4389555 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QI031_RS19300 (QI031_19300) 4384596..4385051 - 456 WP_281481272.1 transcriptional repressor -
QI031_RS19305 (QI031_19305) 4385826..4386029 + 204 WP_281481273.1 ChaB family protein -
QI031_RS19310 (QI031_19310) 4386056..4387495 - 1440 WP_281481274.1 FAD-binding domain-containing protein -
QI031_RS19315 (QI031_19315) 4387634..4388539 - 906 WP_281481275.1 LD-carboxypeptidase -
QI031_RS19320 (QI031_19320) 4389019..4389318 - 300 WP_281481276.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QI031_RS19325 (QI031_19325) 4389322..4389555 - 234 WP_281481277.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
QI031_RS19330 (QI031_19330) 4390352..4393477 + 3126 WP_281481278.1 zinc-dependent metalloprotease -
QI031_RS19335 (QI031_19335) 4393690..4394220 + 531 WP_281481279.1 PEP-CTERM sorting domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(1-76)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11990.70 Da        Isoelectric Point: 7.9186

>T280845 WP_281481276.1 NZ_CP124543:c4389318-4389019 [Halotia branconii CENA392]
MSLFRLTELAKQDLLSIGRYTQKTWGIEQRNRYLTMLDDCFQILARNPHKGRACDEISPGYRKYHIGRHLIFYRETDEYI
DIVRILHDRMDIESHFNKD

Download         Length: 300 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8488.45 Da        Isoelectric Point: 4.4423

>AT280845 WP_281481277.1 NZ_CP124543:c4389555-4389322 [Halotia branconii CENA392]
MQKNTSVTLGEHFEAFIASQIESGRFNSASEAIRAGLRLLEEREIKLAALQRALTEGENSGFTDYSLSGLLAELDRE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References