Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4137138..4137750 Replicon chromosome
Accession NZ_CP124543
Organism Halotia branconii CENA392

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QI031_RS18185 Protein ID WP_281481066.1
Coordinates 4137138..4137515 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QI031_RS18190 Protein ID WP_281481067.1
Coordinates 4137508..4137750 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QI031_RS18155 (QI031_18155) 4132796..4133008 + 213 WP_281481060.1 hypothetical protein -
QI031_RS18160 (QI031_18160) 4133075..4133962 - 888 WP_281481061.1 site-specific DNA-methyltransferase -
QI031_RS18165 (QI031_18165) 4134140..4135666 - 1527 WP_281481062.1 ferredoxin:protochlorophyllide reductase (ATP-dependent) subunit B -
QI031_RS18170 (QI031_18170) 4136100..4136309 - 210 WP_281481063.1 hypothetical protein -
QI031_RS18175 (QI031_18175) 4136445..4137026 - 582 WP_281481064.1 Uma2 family endonuclease -
QI031_RS18180 (QI031_18180) 4137023..4137160 - 138 WP_281481065.1 hypothetical protein -
QI031_RS18185 (QI031_18185) 4137138..4137515 - 378 WP_281481066.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QI031_RS18190 (QI031_18190) 4137508..4137750 - 243 WP_281481067.1 hypothetical protein Antitoxin
QI031_RS18195 (QI031_18195) 4137768..4139930 - 2163 WP_281481068.1 N-6 DNA methylase -
QI031_RS18200 (QI031_18200) 4139987..4141336 - 1350 WP_281481069.1 type I restriction enzyme HsdR N-terminal domain-containing protein -
QI031_RS18205 (QI031_18205) 4141518..4141643 + 126 WP_281481070.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(23-108)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14144.21 Da        Isoelectric Point: 9.7522

>T280844 WP_281481066.1 NZ_CP124543:c4137515-4137138 [Halotia branconii CENA392]
MVDQPLIQVQASPTFKRNIRALAKKYRSIRNDIQPVIEQLQQGELSGDQIPGVGYAIFKLRVRNSDAQKGKSGGYRLIYY
VKTATGIILLTVYTKSKQVDIAAKDIQSIIAEYEQQTINDEERDI

Download         Length: 378 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9007.17 Da        Isoelectric Point: 4.0406

>AT280844 WP_281481067.1 NZ_CP124543:c4137750-4137508 [Halotia branconii CENA392]
MKALKVMATINDQGQLTLDHPLLTDKNSRVEVIVLIPEEEEVLDDQSQVEVLADFRQAWHEAMTGHTIPVAQLWEGLEDG

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References