Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 3947821..3948334 Replicon chromosome
Accession NZ_CP124543
Organism Halotia branconii CENA392

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag QI031_RS17295 Protein ID WP_281480896.1
Coordinates 3948068..3948334 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QI031_RS17290 Protein ID WP_281480895.1
Coordinates 3947821..3948075 (+) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QI031_RS17265 (QI031_17265) 3943343..3943606 - 264 WP_281480890.1 hypothetical protein -
QI031_RS17270 (QI031_17270) 3943672..3944628 - 957 WP_281480891.1 hypothetical protein -
QI031_RS17275 (QI031_17275) 3944660..3945553 - 894 WP_281480892.1 tetratricopeptide repeat protein -
QI031_RS17280 (QI031_17280) 3945550..3946410 - 861 WP_281480893.1 hypothetical protein -
QI031_RS17285 (QI031_17285) 3946329..3947237 - 909 WP_281480894.1 SAM-dependent methyltransferase -
QI031_RS17290 (QI031_17290) 3947821..3948075 + 255 WP_281480895.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QI031_RS17295 (QI031_17295) 3948068..3948334 + 267 WP_281480896.1 Txe/YoeB family addiction module toxin Toxin
QI031_RS17300 (QI031_17300) 3948414..3949781 - 1368 WP_281480897.1 AAA-like domain-containing protein -
QI031_RS17305 (QI031_17305) 3950017..3950370 + 354 WP_281480898.1 hypothetical protein -
QI031_RS17310 (QI031_17310) 3950956..3951192 - 237 WP_281480899.1 DUF4327 family protein -
QI031_RS17315 (QI031_17315) 3951787..3951960 - 174 WP_281480900.1 hypothetical protein -
QI031_RS17320 (QI031_17320) 3952093..3953280 - 1188 WP_281480901.1 serine/threonine protein kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(7-86)

Antitoxin

(1-74)


Sequences


Toxin        


Download         Length: 89 a.a.        Molecular weight: 10645.16 Da        Isoelectric Point: 6.9759

>T280843 WP_281480896.1 NZ_CP124543:3948068-3948334 [Halotia branconii CENA392]
MTRKLAWTDEAWNDYLYWQGQDKKILKRINKLIEATIQLPFEGIGKPELLRENLAGFWSRRIDDTNRLVYAVNDEYLTII
SCRYHYFD

Download         Length: 267 bp


Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9384.73 Da        Isoelectric Point: 5.0348

>AT280843 WP_281480895.1 NZ_CP124543:3947821-3948075 [Halotia branconii CENA392]
MKVVTFSEARSNLKTVLDQVVEDVDYTIITRRDAEDAVVMSLELFNSLLETVHLLKSPANAAHLERSIAQFKQGKVVGQN
LLND

Download         Length: 255 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References