Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
Location | 3350364..3351208 | Replicon | chromosome |
Accession | NZ_CP124543 | ||
Organism | Halotia branconii CENA392 |
Toxin (Protein)
Gene name | hepT | Uniprot ID | - |
Locus tag | QI031_RS14660 | Protein ID | WP_281485847.1 |
Coordinates | 3350364..3350765 (-) | Length | 134 a.a. |
Antitoxin (Protein)
Gene name | mntA | Uniprot ID | - |
Locus tag | QI031_RS14665 | Protein ID | WP_281485848.1 |
Coordinates | 3350771..3351208 (-) | Length | 146 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QI031_RS14650 (QI031_14650) | 3345941..3346957 | - | 1017 | WP_281485845.1 | type I-D CRISPR-associated protein Cas7/Csc2 | - |
QI031_RS14655 (QI031_14655) | 3346994..3350329 | - | 3336 | WP_281485846.1 | type I-D CRISPR-associated protein Cas10d/Csc3 | - |
QI031_RS14660 (QI031_14660) | 3350364..3350765 | - | 402 | WP_281485847.1 | DUF86 domain-containing protein | Toxin |
QI031_RS14665 (QI031_14665) | 3350771..3351208 | - | 438 | WP_281485848.1 | nucleotidyltransferase domain-containing protein | Antitoxin |
QI031_RS14670 (QI031_14670) | 3351247..3352266 | - | 1020 | WP_281485849.1 | PDDEXK nuclease domain-containing protein | - |
QI031_RS14675 (QI031_14675) | 3352259..3352483 | - | 225 | WP_281485850.1 | DUF433 domain-containing protein | - |
QI031_RS14680 (QI031_14680) | 3352782..3354971 | - | 2190 | WP_281485851.1 | type I-D CRISPR-associated helicase Cas3' | - |
QI031_RS14685 (QI031_14685) | 3355072..3355938 | + | 867 | WP_281485852.1 | WYL domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 15308.55 Da Isoelectric Point: 5.1442
>T280842 WP_281485847.1 NZ_CP124543:c3350765-3350364 [Halotia branconii CENA392]
MTKIDTVIVTTRLDFIARYLDNLKRFEQVNLDDYLVDFDTQLITERLLQLMAQAAIDINDHILSKLNPGKSETNFDSFIS
LGKYGVITPALARQIAPSSGLRNRLVHEYDEIDPQQVFNSISFALRLYPLYVR
MTKIDTVIVTTRLDFIARYLDNLKRFEQVNLDDYLVDFDTQLITERLLQLMAQAAIDINDHILSKLNPGKSETNFDSFIS
LGKYGVITPALARQIAPSSGLRNRLVHEYDEIDPQQVFNSISFALRLYPLYVR
Download Length: 402 bp
Antitoxin
Download Length: 146 a.a. Molecular weight: 17051.78 Da Isoelectric Point: 6.7191
>AT280842 WP_281485848.1 NZ_CP124543:c3351208-3350771 [Halotia branconii CENA392]
MTTPTITKLREFAQQLPEKIPYLKMLVLFGSRATGDIHAKSDWDFAVLCDQEQREAYVKDNAFLLFELPMVLGKVFKINS
DQIDIVELNQCSELISHFVARDGKVLYEDNPEEFEKFKQKMLLSNSELKKIEHLKRRNIEKFLQR
MTTPTITKLREFAQQLPEKIPYLKMLVLFGSRATGDIHAKSDWDFAVLCDQEQREAYVKDNAFLLFELPMVLGKVFKINS
DQIDIVELNQCSELISHFVARDGKVLYEDNPEEFEKFKQKMLLSNSELKKIEHLKRRNIEKFLQR
Download Length: 438 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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