Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 3350364..3351208 Replicon chromosome
Accession NZ_CP124543
Organism Halotia branconii CENA392

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag QI031_RS14660 Protein ID WP_281485847.1
Coordinates 3350364..3350765 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag QI031_RS14665 Protein ID WP_281485848.1
Coordinates 3350771..3351208 (-) Length 146 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QI031_RS14650 (QI031_14650) 3345941..3346957 - 1017 WP_281485845.1 type I-D CRISPR-associated protein Cas7/Csc2 -
QI031_RS14655 (QI031_14655) 3346994..3350329 - 3336 WP_281485846.1 type I-D CRISPR-associated protein Cas10d/Csc3 -
QI031_RS14660 (QI031_14660) 3350364..3350765 - 402 WP_281485847.1 DUF86 domain-containing protein Toxin
QI031_RS14665 (QI031_14665) 3350771..3351208 - 438 WP_281485848.1 nucleotidyltransferase domain-containing protein Antitoxin
QI031_RS14670 (QI031_14670) 3351247..3352266 - 1020 WP_281485849.1 PDDEXK nuclease domain-containing protein -
QI031_RS14675 (QI031_14675) 3352259..3352483 - 225 WP_281485850.1 DUF433 domain-containing protein -
QI031_RS14680 (QI031_14680) 3352782..3354971 - 2190 WP_281485851.1 type I-D CRISPR-associated helicase Cas3' -
QI031_RS14685 (QI031_14685) 3355072..3355938 + 867 WP_281485852.1 WYL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(17-122)

Antitoxin

Polymerase beta, nucleotidyltransferase

(18-111)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15308.55 Da        Isoelectric Point: 5.1442

>T280842 WP_281485847.1 NZ_CP124543:c3350765-3350364 [Halotia branconii CENA392]
MTKIDTVIVTTRLDFIARYLDNLKRFEQVNLDDYLVDFDTQLITERLLQLMAQAAIDINDHILSKLNPGKSETNFDSFIS
LGKYGVITPALARQIAPSSGLRNRLVHEYDEIDPQQVFNSISFALRLYPLYVR

Download         Length: 402 bp

Antitoxin


Download         Length: 146 a.a.        Molecular weight: 17051.78 Da        Isoelectric Point: 6.7191

>AT280842 WP_281485848.1 NZ_CP124543:c3351208-3350771 [Halotia branconii CENA392]
MTTPTITKLREFAQQLPEKIPYLKMLVLFGSRATGDIHAKSDWDFAVLCDQEQREAYVKDNAFLLFELPMVLGKVFKINS
DQIDIVELNQCSELISHFVARDGKVLYEDNPEEFEKFKQKMLLSNSELKKIEHLKRRNIEKFLQR

Download         Length: 438 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References