Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1975427..1975910 Replicon chromosome
Accession NZ_CP124543
Organism Halotia branconii CENA392

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag QI031_RS08740 Protein ID WP_281484795.1
Coordinates 1975427..1975690 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag QI031_RS08745 Protein ID WP_281484796.1
Coordinates 1975680..1975910 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QI031_RS08715 (QI031_08715) 1970946..1971872 - 927 WP_281485965.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
QI031_RS08720 (QI031_08720) 1971899..1972774 - 876 WP_281484792.1 lipoyl synthase -
QI031_RS08730 (QI031_08730) 1974526..1974675 + 150 WP_281484793.1 hypothetical protein -
QI031_RS08735 (QI031_08735) 1974675..1975430 + 756 WP_281484794.1 PDDEXK nuclease domain-containing protein -
QI031_RS08740 (QI031_08740) 1975427..1975690 + 264 WP_281484795.1 BrnT family toxin Toxin
QI031_RS08745 (QI031_08745) 1975680..1975910 + 231 WP_281484796.1 CopG family transcriptional regulator Antitoxin
QI031_RS08750 (QI031_08750) 1975907..1976188 + 282 WP_281484797.1 type I restriction endonuclease subunit R -
QI031_RS08755 (QI031_08755) 1976320..1976688 + 369 WP_281484798.1 hypothetical protein -
QI031_RS08760 (QI031_08760) 1976685..1976897 - 213 Protein_1734 hypothetical protein -
QI031_RS08765 (QI031_08765) 1976964..1977769 + 806 Protein_1735 IS5 family transposase -
QI031_RS08770 (QI031_08770) 1978371..1979864 + 1494 WP_281484799.1 VanZ family protein -
QI031_RS08775 (QI031_08775) 1979966..1980721 - 756 WP_281484800.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10420.75 Da        Isoelectric Point: 6.2229

>T280841 WP_281484795.1 NZ_CP124543:1975427-1975690 [Halotia branconii CENA392]
MTVFEYDENKSQSNFVKHGIDFIEAQKLWNDPNLLEIPARTQDELRFLVIAKIDNKHWSRVITYRDQNIRIISVHRSRTE
EIALYDS

Download         Length: 264 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8612.87 Da        Isoelectric Point: 4.3855

>AT280841 WP_281484796.1 NZ_CP124543:1975680-1975910 [Halotia branconii CENA392]
MTAKEFDQKFDDGEDITEMLDLSKAKRPLSAQKKVSIELPIWMIELIDQEANRLGVTPQTIIQTFLAEHLAVNNPS

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References