280838

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4691585..4691948 Replicon chromosome
Accession NZ_CP124533
Organism Xanthomonas campestris strain JN

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag QJS72_RS20740 Protein ID WP_011270059.1
Coordinates 4691585..4691719 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag QJS72_RS20745 Protein ID WP_011038999.1
Coordinates 4691796..4691948 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJS72_RS20720 4686850..4688502 - 1653 WP_172973909.1 M28 family metallopeptidase -
QJS72_RS20725 4688666..4689610 - 945 WP_172973853.1 MBL fold metallo-hydrolase -
QJS72_RS20730 4689694..4690983 - 1290 WP_172973854.1 tryptophan--tRNA ligase -
QJS72_RS20735 4691143..4691352 - 210 WP_011038998.1 CsbD family protein -
QJS72_RS20740 4691585..4691719 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
QJS72_RS20745 4691796..4691948 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
QJS72_RS20750 4692059..4692982 - 924 Protein_4016 arginase -
QJS72_RS20755 4693296..4693757 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
QJS72_RS20760 4693840..4694199 + 360 WP_011039002.1 hypothetical protein -
QJS72_RS20765 4694302..4695219 + 918 WP_011039003.1 hypothetical protein -
QJS72_RS20770 4695216..4695758 + 543 WP_011039004.1 GTPase -
QJS72_RS20775 4696093..4696776 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T280838 WP_011270059.1 NZ_CP124533:c4691719-4691585 [Xanthomonas campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp


Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT280838 WP_011038999.1 NZ_CP124533:c4691948-4691796 [Xanthomonas campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0


Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References