Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1235358..1236136 Replicon chromosome
Accession NZ_CP124531
Organism Xanthomonas campestris strain TJ

Toxin (Protein)


Gene name TacT2 Uniprot ID Q8P667
Locus tag QJS71_RS05245 Protein ID WP_011038220.1
Coordinates 1235358..1235849 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID Q8P668
Locus tag QJS71_RS05250 Protein ID WP_011038219.1
Coordinates 1235846..1236136 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJS71_RS05225 1231609..1232484 + 876 WP_016945000.1 30S ribosomal protein S6--L-glutamate ligase -
QJS71_RS05230 1232707..1233180 + 474 WP_012437597.1 hypothetical protein -
QJS71_RS05235 1233211..1233888 + 678 WP_003490678.1 response regulator transcription factor -
QJS71_RS05240 1233881..1235215 + 1335 WP_012437598.1 HAMP domain-containing sensor histidine kinase -
QJS71_RS05245 1235358..1235849 - 492 WP_011038220.1 GNAT family N-acetyltransferase Toxin
QJS71_RS05250 1235846..1236136 - 291 WP_011038219.1 DUF1778 domain-containing protein Antitoxin
QJS71_RS05255 1236211..1236612 - 402 WP_019237348.1 SymE family type I addiction module toxin -
QJS71_RS05260 1237144..1237767 - 624 WP_011038217.1 dephospho-CoA kinase -
QJS71_RS05265 1237781..1238644 - 864 WP_011038216.1 A24 family peptidase -
QJS71_RS05270 1238651..1239907 - 1257 WP_011038215.1 type II secretion system F family protein -
QJS71_RS05275 1240234..1240674 + 441 WP_011038214.1 pilin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1192357..1238944 46587


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17638.31 Da        Isoelectric Point: 8.1192

>T280835 WP_011038220.1 NZ_CP124531:c1235849-1235358 [Xanthomonas campestris]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL

Download         Length: 492 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10678.23 Da        Isoelectric Point: 10.5480

>AT280835 WP_011038219.1 NZ_CP124531:c1236136-1235846 [Xanthomonas campestris]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLITASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q8P667

Antitoxin

Source ID Structure
AlphaFold DB Q8P668

References