280834

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4653310..4653673 Replicon chromosome
Accession NZ_CP124530
Organism Xanthomonas campestris strain YX

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag QJS69_RS20565 Protein ID WP_011270059.1
Coordinates 4653310..4653444 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag QJS69_RS20570 Protein ID WP_011038999.1
Coordinates 4653521..4653673 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJS69_RS20545 4648574..4650226 - 1653 WP_043890286.1 M28 family metallopeptidase -
QJS69_RS20550 4650391..4651335 - 945 WP_043890287.1 MBL fold metallo-hydrolase -
QJS69_RS20555 4651419..4652708 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
QJS69_RS20560 4652868..4653077 - 210 WP_011038998.1 CsbD family protein -
QJS69_RS20565 4653310..4653444 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
QJS69_RS20570 4653521..4653673 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
QJS69_RS20575 4653784..4654707 - 924 WP_012439504.1 arginase -
QJS69_RS20580 4655021..4655482 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
QJS69_RS20585 4655565..4655924 + 360 WP_011039002.1 hypothetical protein -
QJS69_RS20590 4656027..4656944 + 918 WP_012439506.1 hypothetical protein -
QJS69_RS20595 4656941..4657483 + 543 WP_012439507.1 GTPase -
QJS69_RS20600 4657818..4658501 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T280834 WP_011270059.1 NZ_CP124530:c4653444-4653310 [Xanthomonas campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp


Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT280834 WP_011038999.1 NZ_CP124530:c4653673-4653521 [Xanthomonas campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0


Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References