Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1243452..1244230 Replicon chromosome
Accession NZ_CP124530
Organism Xanthomonas campestris strain YX

Toxin (Protein)


Gene name TacT2 Uniprot ID Q8P667
Locus tag QJS69_RS05295 Protein ID WP_011038220.1
Coordinates 1243452..1243943 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID Q8P668
Locus tag QJS69_RS05300 Protein ID WP_011038219.1
Coordinates 1243940..1244230 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJS69_RS05275 1239703..1240578 + 876 WP_016945000.1 30S ribosomal protein S6--L-glutamate ligase -
QJS69_RS05280 1240801..1241274 + 474 WP_012437597.1 hypothetical protein -
QJS69_RS05285 1241305..1241982 + 678 WP_003490678.1 response regulator transcription factor -
QJS69_RS05290 1241975..1243309 + 1335 WP_012437598.1 HAMP domain-containing sensor histidine kinase -
QJS69_RS05295 1243452..1243943 - 492 WP_011038220.1 GNAT family N-acetyltransferase Toxin
QJS69_RS05300 1243940..1244230 - 291 WP_011038219.1 DUF1778 domain-containing protein Antitoxin
QJS69_RS05305 1244305..1244706 - 402 WP_012437599.1 SymE family type I addiction module toxin -
QJS69_RS05310 1245238..1245861 - 624 WP_011038217.1 dephospho-CoA kinase -
QJS69_RS05315 1245875..1246738 - 864 WP_012437600.1 A24 family peptidase -
QJS69_RS05320 1246745..1248004 - 1260 WP_012437601.1 type II secretion system F family protein -
QJS69_RS05325 1248356..1248769 + 414 WP_012437602.1 pilin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17638.31 Da        Isoelectric Point: 8.1192

>T280833 WP_011038220.1 NZ_CP124530:c1243943-1243452 [Xanthomonas campestris]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL

Download         Length: 492 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10678.23 Da        Isoelectric Point: 10.5480

>AT280833 WP_011038219.1 NZ_CP124530:c1244230-1243940 [Xanthomonas campestris]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLITASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q8P667

Antitoxin

Source ID Structure
AlphaFold DB Q8P668

References