Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelB-YoeB
Location 24346..24887 Replicon plasmid pWB2
Accession NZ_CP124527
Organism Psychrobacter sp. WB2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QJS82_RS13575 Protein ID WP_087813576.1
Coordinates 24346..24636 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QJS82_RS13580 Protein ID WP_087813577.1
Coordinates 24633..24887 (+) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJS82_RS13545 (QJS82_13545) 20107..20580 + 474 WP_000777554.1 trimethoprim-resistant dihydrofolate reductase DfrA1 -
QJS82_RS13550 (QJS82_13550) 20675..21199 + 525 WP_000704156.1 streptothricin N-acetyltransferase Sat2 -
QJS82_RS13555 (QJS82_13555) 21257..22092 + 836 Protein_23 ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1 -
QJS82_RS13560 (QJS82_13560) 22121..22618 + 498 WP_001444089.1 hypothetical protein -
QJS82_RS13565 (QJS82_13565) 22679..23050 + 372 WP_000119696.1 hypothetical protein -
QJS82_RS13570 (QJS82_13570) 23460..23654 + 195 Protein_26 hypothetical protein -
QJS82_RS13575 (QJS82_13575) 24346..24636 + 291 WP_087813576.1 type II toxin-antitoxin system prevent-host-death family antitoxin Toxin
QJS82_RS13580 (QJS82_13580) 24633..24887 + 255 WP_087813577.1 Txe/YoeB family addiction module toxin Antitoxin
QJS82_RS13585 (QJS82_13585) 26065..27033 - 969 WP_281491739.1 DNA-binding protein -
QJS82_RS13590 (QJS82_13590) 27292..27456 - 165 WP_156410068.1 hypothetical protein -
QJS82_RS13595 (QJS82_13595) 27443..27731 - 289 Protein_31 BrnT family toxin -
QJS82_RS13600 (QJS82_13600) 27728..27955 - 228 WP_058368521.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
QJS82_RS13605 (QJS82_13605) 28039..28995 - 957 WP_058368520.1 replication initiation protein -
QJS82_RS13610 (QJS82_13610) 29322..29492 - 171 WP_156410067.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid sul2 / floR / dfrA1 / ant(3'')-Ia - 1..44871 44871


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-74)

Antitoxin

(5-84)


Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 10960.45 Da        Isoelectric Point: 4.8948

>T280831 WP_087813576.1 NZ_CP124527:24346-24636 [Psychrobacter sp. WB2]
MDVVNYTDFRKSLAKYIDKVDTDKGPILITRQNAKPTVLMSLEEFNSYEETLHLLSSPTNAKRLRRSIADAKAGRLIERE
IDAKDMPLTFDDEVDA

Download         Length: 291 bp


Antitoxin


Download         Length: 85 a.a.        Molecular weight: 10237.74 Da        Isoelectric Point: 8.0267

>AT280831 WP_087813577.1 NZ_CP124527:24633-24887 [Psychrobacter sp. WB2]
MILSWTEDAWEDYEYWQRTSKEKVKQIGKLIKAIKRDPFKGIGKPEPLKHDLAGYWSRRIDQEHRLVYEIQDDAIIIVQC
RYHY

Download         Length: 255 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References