Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | V | Classification (family/domain) | ghoTS/ghoT-GhoS |
Location | 4498950..4499447 | Replicon | chromosome |
Accession | NZ_CP124506 | ||
Organism | Escherichia coli strain AVS0750 |
Toxin (Protein)
Gene name | ghoT | Uniprot ID | L4JJG6 |
Locus tag | QJP88_RS22045 | Protein ID | WP_001173343.1 |
Coordinates | 4498950..4499123 (-) | Length | 58 a.a. |
Antitoxin (Protein)
Gene name | ghoS | Uniprot ID | S1NQ59 |
Locus tag | QJP88_RS22050 | Protein ID | WP_001312331.1 |
Coordinates | 4499151..4499447 (-) | Length | 99 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QJP88_RS22035 (4495620) | 4495620..4497077 | + | 1458 | WP_000856826.1 | dipeptide/tripeptide permease DtpC | - |
QJP88_RS22040 (4497314) | 4497314..4498831 | + | 1518 | WP_000003806.1 | lysine--tRNA ligase | - |
QJP88_RS22045 (4498950) | 4498950..4499123 | - | 174 | WP_001173343.1 | type V toxin-antitoxin system toxin GhoT | Toxin |
QJP88_RS22050 (4499151) | 4499151..4499447 | - | 297 | WP_001312331.1 | type V toxin-antitoxin system endoribonuclease antitoxin GhoS | Antitoxin |
QJP88_RS22055 (4499675) | 4499675..4499947 | - | 273 | WP_000405643.1 | GNAT family N-acetyltransferase | - |
QJP88_RS22060 (4500161) | 4500161..4504090 | - | 3930 | WP_001080127.1 | autotransporter outer membrane beta-barrel domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 4474207..4515130 | 40923 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QI41 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | S1NQ59 |