Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | paaR-paaA-parE/- |
Location | 2126319..2126790 | Replicon | chromosome |
Accession | NZ_CP124481 | ||
Organism | Escherichia coli strain AVS0756 |
Toxin (Protein)
Gene name | parE_1 | Uniprot ID | A0A0D7C2L1 |
Locus tag | QJP55_RS10220 | Protein ID | WP_001303511.1 |
Coordinates | 2126319..2126597 (-) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | paaA | Uniprot ID | Q8XAD5 |
Locus tag | QJP55_RS10225 | Protein ID | WP_001302048.1 |
Coordinates | 2126599..2126790 (-) | Length | 64 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QJP55_RS10185 (2121532) | 2121532..2121801 | - | 270 | WP_000003742.1 | excisionase | - |
QJP55_RS10190 (2121863) | 2121863..2124301 | - | 2439 | WP_000102132.1 | exonuclease | - |
QJP55_RS10195 (2124394) | 2124394..2124582 | - | 189 | WP_000199475.1 | DUF1482 family protein | - |
QJP55_RS10200 (2124579) | 2124579..2124767 | - | 189 | WP_000449175.1 | cell division inhibition protein DicB | - |
QJP55_RS10205 (2125343) | 2125343..2125537 | + | 195 | WP_001295058.1 | hypothetical protein | - |
QJP55_RS10210 (2125526) | 2125526..2125864 | - | 339 | WP_000394541.1 | hypothetical protein | - |
QJP55_RS10215 (2125876) | 2125876..2126028 | - | 153 | WP_000380313.1 | DUF1391 family protein | - |
QJP55_RS10220 (2126319) | 2126319..2126597 | - | 279 | WP_001303511.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
QJP55_RS10225 (2126599) | 2126599..2126790 | - | 192 | WP_001302048.1 | hypothetical protein | Antitoxin |
QJP55_RS10230 (2126811) | 2126811..2127182 | - | 372 | WP_001169687.1 | hypothetical protein | - |
QJP55_RS10235 (2127280) | 2127280..2127582 | + | 303 | WP_001556930.1 | transcriptional regulator | - |
QJP55_RS10240 (2127579) | 2127579..2128004 | + | 426 | WP_000693943.1 | toxin YdaT family protein | - |
QJP55_RS10245 (2128027) | 2128027..2128989 | + | 963 | WP_000095673.1 | helix-turn-helix domain-containing protein | - |
QJP55_RS10250 (2128996) | 2128996..2129742 | + | 747 | WP_000788950.1 | ATP-binding protein | - |
QJP55_RS10255 (2129764) | 2129764..2130534 | + | 771 | WP_000450998.1 | DUF1627 domain-containing protein | - |
QJP55_RS10260 (2130550) | 2130550..2130972 | + | 423 | Protein_2004 | DUF977 family protein | - |
QJP55_RS10265 (2131078) | 2131078..2131290 | + | 213 | WP_000072553.1 | hypothetical protein | - |
QJP55_RS10270 (2131323) | 2131323..2131541 | + | 219 | WP_001610644.1 | DUF4014 family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 2117922..2145175 | 27253 | |
- | inside | Prophage | sitABCD | - | 2113277..2312175 | 198898 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
PDB | 5CZF | |
PDB | 5CW7 | |
PDB | 5CZE |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829CTP0 |