Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | yeeUV (cbtA-cbeA)/CbtA-CbeA |
| Location | 822206..823040 | Replicon | chromosome |
| Accession | NZ_CP124471 | ||
| Organism | Escherichia coli strain AVS0973 | ||
Toxin (Protein)
| Gene name | yeeV | Uniprot ID | - |
| Locus tag | QJP95_RS03990 | Protein ID | WP_001546109.1 |
| Coordinates | 822206..822583 (-) | Length | 126 a.a. |
Antitoxin (Protein)
| Gene name | yeeU | Uniprot ID | A0A7I0L0C8 |
| Locus tag | QJP95_RS03995 | Protein ID | WP_001546108.1 |
| Coordinates | 822660..823040 (-) | Length | 127 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QJP95_RS03960 (818600) | 818600..818770 | - | 171 | Protein_778 | IS110 family transposase | - |
| QJP95_RS03965 (819187) | 819187..820121 | - | 935 | Protein_779 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| QJP95_RS03970 (820114) | 820114..820509 | - | 396 | WP_000208383.1 | DUF6088 family protein | - |
| QJP95_RS03975 (820578) | 820578..821423 | - | 846 | WP_001280441.1 | DUF4942 domain-containing protein | - |
| QJP95_RS03980 (821508) | 821508..821705 | - | 198 | WP_000839260.1 | DUF957 domain-containing protein | - |
| QJP95_RS03985 (821722) | 821722..822209 | - | 488 | Protein_783 | DUF5983 family protein | - |
| QJP95_RS03990 (822206) | 822206..822583 | - | 378 | WP_001546109.1 | TA system toxin CbtA family protein | Toxin |
| QJP95_RS03995 (822660) | 822660..823040 | - | 381 | WP_001546108.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin |
| QJP95_RS04000 (823090) | 823090..823734 | - | 645 | WP_000086755.1 | hypothetical protein | - |
| QJP95_RS04005 (823753) | 823753..823974 | - | 222 | WP_000692345.1 | DUF987 domain-containing protein | - |
| QJP95_RS04010 (824043) | 824043..824519 | - | 477 | WP_001424026.1 | RadC family protein | - |
| QJP95_RS04015 (824535) | 824535..825020 | - | 486 | WP_000849588.1 | antirestriction protein | - |
| QJP95_RS04020 (825075) | 825075..825893 | - | 819 | WP_001234620.1 | DUF932 domain-containing protein | - |
| QJP95_RS04025 (825993) | 825993..826226 | - | 234 | WP_001119729.1 | DUF905 family protein | - |
| QJP95_RS04030 (826305) | 826305..826760 | - | 456 | WP_001545736.1 | IrmA family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 126 a.a. Molecular weight: 13986.00 Da Isoelectric Point: 8.5190
>T280404 WP_001546109.1 NZ_CP124471:c822583-822206 [Escherichia coli]
MKTLPDTHVRAASRCPSPVTIWQTLLTQLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
SAGAPSQLINSIDILRARRATGLMTRNNYKMVNNITQGKHPEAKR
MKTLPDTHVRAASRCPSPVTIWQTLLTQLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
SAGAPSQLINSIDILRARRATGLMTRNNYKMVNNITQGKHPEAKR
Download Length: 378 bp
Antitoxin
Download Length: 127 a.a. Molecular weight: 13997.78 Da Isoelectric Point: 5.0823
>AT280404 WP_001546108.1 NZ_CP124471:c823040-822660 [Escherichia coli]
MSDTLPGTTLPDDNKDRPWWGLPCTVTPCFGARLVQEGNRLHYLADRAGIRGRFNNADAYHLDQAFPLLMKQLELMLTSG
ELNPRHQHTVTLYAKGLTCDADTLGSCGYVYLAVYPATETESNPPE
MSDTLPGTTLPDDNKDRPWWGLPCTVTPCFGARLVQEGNRLHYLADRAGIRGRFNNADAYHLDQAFPLLMKQLELMLTSG
ELNPRHQHTVTLYAKGLTCDADTLGSCGYVYLAVYPATETESNPPE
Download Length: 381 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|